Top Research Papers on Diabetes

The American Diabetes Association (ADA) "Standards of Care in Diabetes" includes the ADA's current clinical practice recommendations and is intended to provide the components of diabetes care, general treatment goals and guidelines, and tools to evaluate quality of care. Members of the ADA Professional Practice Committee, an interprofessional expert committee, are responsible for updating the Standards of Care annually, or more frequently as warranted. For a detailed description of ADA standards, statements, and reports, as well as the evidence-grading system for ADA's clinical practice recomm...

The American Diabetes Association (ADA) "Standards of Care in Diabetes" includes the ADA's current clinical practice recommendations and is intended to provide the components of diabetes care, general treatment goals and guidelines, and tools to evaluate quality of care. Members of the ADA Professional Practice Committee, a multidisciplinary expert committee, are responsible for updating the Standards of Care annually, or more frequently as warranted. For a detailed description of ADA standards, statements, and reports, as well as the evidence-grading system for ADA's clinical practice recomme...

Guava, also known as Psidiumguajava L., is a vital tropical food plant with a range of therapeutic uses and contains bioactive constituents including polyphenols, flavonoids, and heteropolysaccharides that are found to be antihyperglycemic properties.

In DN patients, the severity of DR was associated with glomerular injury, and presence of KW nodules, lower hemoglobin levels and younger age were independent risk factors associated with more severe DR in patients with DN.

The American Diabetes Association (ADA) "Standards of Care in Diabetes" includes the ADA's current clinical practice recommendations and is intended to provide the components of diabetes care, general treatment goals and guidelines, and tools to evaluate quality of care. Members of the ADA Professional Practice Committee, an interprofessional expert committee, are responsible for updating the Standards of Care annually, or more frequently as warranted. For a detailed description of ADA standards, statements, and reports, as well as the evidence-grading system for ADA's clinical practice recomm...

The American Diabetes Association (ADA) "Standards of Medical Care in Diabetes" includes the ADA's current clinical practice recommendations and is intended to provide the components of diabetes care, general treatment goals and guidelines, and tools to evaluate quality of care.

Diabetic foot ulcers affect approximately 18.6 million people worldwide each year and are associated with increased rates of amputation and death, and randomized clinical trials support treatments to accelerate wound healing and culture-directed oral antibiotics for localized osteomyelitis.

A panel to update the previous consensus statements on the management of hyperglycemia in type 2 diabetes in adults, published since 2006 and last updated in 2019, concludes that there is a greater emphasis on weight management as part of the holistic approach to diabetes management.

It is concluded that in 2021 more than 1 in 10 adults worldwide developed diabetes, and the incidence of diabetes in the world, Southeast Asia, and India was 10.5%, 8.8%, and 9.6%, respectively, throughout 2021 and will rise to 12.8% by 2045.

The American Diabetes Association (ADA) "Standards of Care in Diabetes" includes the ADA's current clinical practice recommendations and is intended to provide the components of diabetes care, general treatment goals and guidelines, and tools to evaluate quality of care. Members of the ADA Professional Practice Committee, a multidisciplinary expert committee, are responsible for updating the Standards of Care annually, or more frequently as warranted. For a detailed description of ADA standards, statements, and reports, as well as the evidence-grading system for ADA's clinical practice recomme...

This review particularly focuses on novel targets that may play role in pathogenesis of type 2 diabetes and further research on these targets may eventually pave the way to novel therapies for the treatment—or even the prevention— of type 1 diabetes along with its complications.

This review focuses on HNF1α gene polymorphisms, H NF1A-MODY3, HNF 1A-associated T2D and GDM, and the related pathogenesis and treatment methods and it is hoped this review will provide a valuable reference for the precise and individualized treatment of diabetes caused by abnormal HNF2α.

The types of monogenic diabetes are described, including common and uncommon types of maturity-onset diabetes of the young, multiple causes of neonatal DM, and syndromic diabetes such as Wolfram syndrome and lipodystrophy.

Using multi‐omics analysis, comprehensive molecular mechanisms have been elucidated to guide the development of targeted therapy for type 2 diabetes and diabetic complications and their response to treatment.

The recommended age for diabetes screening has been lowered and recently revised guidelines for managing hypertension and dyslipidemia in patients with diabetes have been incorporated into this guideline.

The American Diabetes Association (ADA) "Standards of Care in Diabetes" includes the ADA's current clinical practice recommendations and is intended to provide the components of diabetes care, general treatment goals and guidelines, and tools to evaluate quality of care. Members of the ADA Professional Practice Committee, an interprofessional expert committee, are responsible for updating the Standards of Care annually, or more frequently as warranted. For a detailed description of ADA standards, statements, and reports, as well as the evidence-grading system for ADA's clinical practice recomm...

The effects of quercetin on the key mechanisms of pathogenesis of diabetes complications including nephropathy, cardiovascular complications, neuropathy, delayed wound healing, and retinopathy are reviewed.

Type 2 diabetes mellitus and pre‐diabetes are associated with reduced circulating testosterone levels. However, the role of testosterone replacement therapy in these patients is still conflicting.

The American Diabetes Association (ADA) "Standards of Care in Diabetes" includes the ADA's current clinical practice recommendations and is intended to provide the components of diabetes care, general treatment goals and guidelines, and tools to evaluate quality of care. Members of the ADA Professional Practice Committee, a multidisciplinary expert committee, are responsible for updating the Standards of Care annually, or more frequently as warranted. For a detailed description of ADA standards, statements, and reports, as well as the evidence-grading system for ADA's clinical practice recomme...

The American Diabetes Association (ADA) "Standards of Care in Diabetes" includes the ADA's current clinical practice recommendations and is intended to provide the components of diabetes care, general treatment goals and guidelines, and tools to evaluate quality of care. Members of the ADA Professional Practice Committee, an interprofessional expert committee, are responsible for updating the Standards of Care annually, or more frequently as warranted. For a detailed description of ADA standards, statements, and reports, as well as the evidence-grading system for ADA's clinical practice recomm...

Examination of the relationship between diabetic retinopathy (DR) and systemic factors revealed a significant correlation between diabetic macular edema (DME) development and DN grade, and decreased renal function predicts the onset of DR.

In patients with preexisting cardiovascular disease and overweight or obesity but without diabetes, weekly subcutaneous semaglutide at a dose of 2.4 mg was superior to placebo in reducing the incidence of death from cardiovascular causes,Nonfatal myocardial infarction, or nonfatal stroke at a mean follow-up of 39.8 months.

This paper presents a meta-analyses of the immune system’s role in the development of type 2 diabetes and its role in mortality and morbidity in patients with diabetes.

The current global state of diabetes, the mechanisms involved in glucose homeostasis and diabetic insulin resistance, and the long-chain non-coding RNA (lncRNA) associated with diabetes are provided.

Patients with DM admitted to hospital with foot infections have worse clinical outcomes during the index hospitalisation and are more likely to have re-infection and re-admission to hospital in the next year.

The American Diabetes Association (ADA) "Standards of Care in Diabetes" includes the ADA's current clinical practice recommendations and is intended to provide the components of diabetes care, general treatment goals and guidelines, and tools to evaluate quality of care. Members of the ADA Professional Practice Committee, a multidisciplinary expert committee, are responsible for updating the Standards of Care annually, or more frequently as warranted. For a detailed description of ADA standards, statements, and reports, as well as the evidence-grading system for ADA's clinical practice recomme...

The American Diabetes Association (ADA) "Standards of Care in Diabetes" includes the ADA's current clinical practice recommendations and is intended to provide the components of diabetes care, general treatment goals and guidelines, and tools to evaluate quality of care. Members of the ADA Professional Practice Committee, an interprofessional expert committee, are responsible for updating the Standards of Care annually, or more frequently as warranted. For a detailed description of ADA standards, statements, and reports, as well as the evidence-grading system for ADA's clinical practice recomm...

The evidence of diabetic choroidopathy in vivo was confirmed with multimodal imaging, which provides key quantitative and qualitative features to characterize the choroidal involvement.

SCORE2-Diabetes, a new algorithm developed, calibrated, and validated to predict 10-year risk of CVD in individuals with type 2 diabetes, enhances identification of individuals at higher risk of developing CVD across Europe.

The American Diabetes Association (ADA) "Standards of Medical Care in Diabetes" includes the ADA's current clinical practice recommendations and is intended to provide the components of diabetes care, general treatment goals and guidelines, and tools to evaluate quality of care.

This study assesses the utility of ChatGPT, an AI chatbot created by OpenAI, in responding to the diabetes knowledge questionnaire (24- DKQ), and found that ChatG PT accurately answered all 24 questions of the 24-DKQ, and was also able to expand and provide decent explanations.

The writing group was aware of both national and international guidance on type 1 Diabetes and did not seek to replicate this but rather aimed to highlight the major areas that health care professionals should consider when managing adults with type 1 diabetes.

This quality improvement study examines the association of a pharmacist-led intervention with HbA1c and systolic blood pressure among Hispanic patients with diabetes.

The American Diabetes Association (ADA) "Standards of Care in Diabetes" includes the ADA's current clinical practice recommendations and is intended to provide the components of diabetes care, general treatment goals and guidelines, and tools to evaluate quality of care. Members of the ADA Professional Practice Committee, an interprofessional expert committee, are responsible for updating the Standards of Care annually, or more frequently as warranted. For a detailed description of ADA standards, statements, and reports, as well as the evidence-grading system for ADA's clinical practice recomm...

The role of adipokines in the pathomechanism of gestational diabetes as well as their potential role in the detection and treatment of this condition are presented.

The scope of this American Diabetes Association consensus report with designated representation from the American College of Cardiology is to provide clear guidance to practitioners on the best approaches for screening and diagnosing HF in individuals with diabetes or prediabetes, to ensure access to optimal, evidence-based management for all.

It is suggested that the increasing risk of DR in children with T2D warrants the implementation of global screening programs at diagnosis and annually to ensure early detection and treatment to preserve vision in this population.

Treatment with a sodium glucose cotransporter 2 (SGLT2) inhibitor is currently one of the most effective treatments for heart failure associated with diabetes, however, an effective treatment for lipotoxicity of the myocardium has not yet been established, and the establishment of aneffective treatment is needed in the future.

Major trends in DR are discussed that the authors expect to see in 2030 and beyond, including new pharmacologic agents targeting other non-VEGF-driven pathways, and novel therapeutic strategies such as gene therapy are being developed for DR.

Results from recent randomized controlled trials on inhibitors of the sodium-glucose cotransporter 2 have determined a paradigm shift in the treatment of patients with type 2 diabetes mellitus, and it is still unclear whether the observed benefits of SGLT2 inhibitors may extend to CKD patients at lower risk of progression and if their association with other agents may confer additional protection.

Approaching diabetes using a systems biology approach by integrating metabolomics with other omics data, such as genetics, transcriptomics, proteomics, and clinical data can present a comprehensive metabolic network and facilitate causal inference and deepen the molecular understanding.

This review incorporates recent findings, demonstrates the diverse functions and regulating mechanisms of Sestrin2, and discusses the potential roles of SESTrin2 in the pathogenesis of diabetes and diabetic complications, hoping to highlight a promising therapeutic direction.

An overview of the relationships between diabetes and stroke, including epidemiology, pathophysiology, post-stroke outcomes, and treatments for people with stroke and diabetes is provided to aid neurologists in diabetes-related decision-making when treating people with acute or recurrent stroke.

The American Diabetes Association (ADA) "Standards of Medical Care in Diabetes" includes the ADA's current clinical practice recommendations and is intended to provide the components of diabetes care, general treatment goals and guidelines, and tools to evaluate quality of care.

A comprehensive systematic review of recent clinical trials and evidence that could be applicable in real-world practice and suitable for the Korean population was performed.

The American Diabetes Association (ADA) "Standards of Medical Care in Diabetes" includes the ADA's current clinical practice recommendations and is intended to provide the components of diabetes care, general treatment goals and guidelines, and tools to evaluate quality of care.

The proposal of this work is to ensure that readers are able to know, interpret, disseminate and in many cases recommend preventive measures that help improve the physical and mental health of readers, and citizens, with this it would be achieved the best quality of life in society.

The possible role of copper in DKD patients is evaluated to assess its influence on diabetes and the progression of its complications, while regulation of adequate serum copper concentration appears to prevent and treat DKD.

The findings of this study suggest that CGM should be encouraged for diabetes management, as it is associated with lower odds of developing DR.

Oleuropein reverses cell apoptosis, regenerates tissues, restores the histological organization, and decreases oxidative stress in treating diabetes complications and can be used as a nutraceutical to fight against these diseases.