Top Research Papers on Genetics PDF

The purpose of the present work is to expand the state of knowledge of the genetic basis of incompatibility in a Honduran isolate of Didym- ium iridis in order to provide a foundation for the next step in the study of incomp compatibility.

The understanding of such complex diseases (and ultimately designing new agents to treat them) is an immense undertaking because of the amount of clinical data needed to produce statistically significant results.

The volume of genetic association studies has increased from a trickle to a veritable cascade, with DNA-based genotyping, the identification of single-nucleotide polymorphisms (SNP), and the completion of the Human Genome Project.

The principal focus of this primer is population-based association studies using unrelated individuals, and much of what is presented is relevant to all types of single-nucleotide polymorphisms (SNPs).

Genetic animal models of alcohol’s effects and alcohol use have greatly advanced the authors' understanding of the genetic basis of alcoholism, resulting in the identification of quantitative trait loci and allowing for targeted manipulation of candidate genes.

Federal regulations, primarily the Common Rule and the Health Insurance Portability and Accountability Act (HIPAA) Privacy Rule, govern the collection, storage, and use of biological specimens for genetic research using banked biological specimens. Despite some prescriptive requirements, the federal law fails to adequately protect individuals’ interests from unwanted collection and use of their tissues for genetic research as a result of ambiguity and limiting the applicability of federal regulation to situations of direct identifiability. Several state legislatures have magnified these loopho...

Genetic researchers are interested in how genes affect the way the authors' bodies work, and they often use blood or saliva samples to look at DNA.

In this issue, Drs Almasy and MacCluer have prepared an editorial, “Association Studies of Vascular Phenotypes: How and Why?” which is intended to provide guidance in understanding and guiding genetic association studies in humans.

To the Editor: I am delighted to see that Arteriosclerosis, Thrombosis, and Vascular Biology has taken the lead in initiating an open discussion about genetic association studies in such a prominent manner.

The data mining is an important algorithm such as genetic algorithm and the results make resources reasonable allocation and solve the problem in the usage of resources.

Genetic algorithm randomly reforms the important gene of code bunch to optimize the new individual bunch and make individual evolve continuously to get optimization result.

A few surnames are being found to include unusually large single families, which are far more populous than computer simulations for monogamous families predict, suggesting that they might best be explained by their getting off to a fast start through polygyny or concubines.

Introducción: con base en el impacto que genera el hallazgo de un feto o recién nacido con alguna alteración cromosómica, desde el punto de vista familiar, social y para las entidades de salud, se analizan los resultados de los estudios genéticos realizados por el Servicio de Perinatología de la Clínica Rafael Uribe Uribe del Instituto de los Seguros Sociales en la ciudad de Cali, durante los últimos seis años. Objetivo: describir la frecuencia de las alteraciones cromosómicas encontradas en la Clínica Rafael Uribe Uribe de Cali durante los estudios genéticos realizados por el Servicio de Peri...

New information about host susceptibility and carcinogenic mechanisms may lead to new means for prevention or early detection of cancer.

It is regarded as a main task for the future to concentrate attention in isolating the effects of major genes, 'rather than to elaboration of non-disprovable hypotheses about the residual cases', and there is a strong recommendation for close co-operation between laboratories for the collection and comparison of very rare cases that are of great potential significance.

It is acknowledged that even in common diseases such as viral bronchiolitis, investigators may struggle to enrol the appropriate numbers of patients, and the recruitment process was time consuming and needed careful planning.

The results suggest no significant difference in the frequency of HLA antigen in the 3 groups.

The aim of this paper is to facilitate future researches such that several proposed modifications in genetic algorithms can be probed quickly.

Evidence is presented to indicate that two separate autosomal dominant genes are involved in spinal muscular atrophy; this disease may be more rapid in its clinical progression.

The methods used to relate genetic variation to individual differences in high-level behaviors such as academic skills and educational achievement are described.