Top Research Papers on Immunology

This review has summarized the knowledge about three members of this group of proteins: Bap of S. aureus, Esp of Enterococcus faecalis and BapA of Salmonella enterica ser.

This review has summarized the knowledge about three members of this group of proteins: Bap of S. aureus, E sp ofEnterococcus faecalis and BapA of Salmonella enterica ser.

Present studies suggest the correlation between immunological disorders and familial or sporadic incidence of febrile seizures and genetic polymorphism of interleukin 1β, 1α and IL-1 antagonist point to some associations between past febrian seizures and manifestation of temporal lobe epilepsy.

The role of autoimmunity and thrombophilia in recurrent implantation failure (RIF) is one of the most controversial issues in assisted reproduction and empiric approach seems to be useless.

The ‘science of immunology’ virtually saw the light of the day through the earnest efforts of Edward Jenner in 1798 who assumed to be true on the basis of reasoning that the value of ‘vaccination’ as a probable means of protection against the cowpox (vaccinia) ailment.

KORA, by binding to KOR, ameliorated ongoing inflammation in the skin as well as the gut and down-regulated the activation of pathogenic effector cells, suggesting KORA as a promising novel compound for the treatment of inflammatory/itchy disorders.

The analysis of this debate elucidates the emergence of a new concept of immunity that rested upon the notion of an active host response, and traces the scientific and logical basis of the initial rejection of the phagocytosis theory.

The structure and function of the lung's immune system and its response to immunologically mediated injury, as well as investigative and diagnostic approaches in immunologic diseases are studied.

The explosive growth of knowledge in immunology during the past few decades and the recognition that the lung is a key player in many immunologic disorders justify the assembly of this material as a single text.

The past year has been characterized by significant novelties from the point of view of the clinical immunologist and the results of the RAVE and RITUXVASC studies have documented that rituximab is a valid alternative to cyclophosphamide in the control of ANCA associated vasculitis.

The mammalian immune system is complex, involving specialised tissues, cells, soluble mediators and membrane-bound molecules and selection pressure by pathogens is believed to drive the generation of polymorphism in functional MHC genes.

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Testosterone exposure alters embryonic bursal gene expression in chicken lines selected for differential antibody response and results suggest that males exposed to testosterone before the second trimester have a lower antibody response than females.

This review will succinctly discuss progress in the understanding of immunological characteristics and behavior of different scaffolds currently under development, with emphasis on the extracellular matrix scaffolds obtained decellularized animal or human organs which seem to provide the ideal template for bioengineering purposes.

Genetic comparisons of Line 72, Line 63 and RCS will help to identify non-Mhc genes that have significant effect on antibody responses, and the overall mean rate of titer decline differed significantly for RCS J and N.

It becomes evident that research in immunology of reproduction is performed with two targets: diagnosis and treatment of the so-called 'immunological sterility', and development of an immunological contraceptive.

Hemodynamic and metabolic changes as seen in diabetic nephropathy are associated with increased TGF-ss expression and extra-cellular matrix expansion in the mesangium and a decrease of podocyte numbers.

Infectious-mediated urticaria appears to be secondary to different types of mast cell activation which could explain the various clinical presentation of the disease.

Essential Immunology Eighth edition, by Ivan M. Roitt is the single author of this book (on a subject he calls delightful), which is available in at least 13 languages other than English.

The data provided from these trials strongly suggest that β-glucans downregulate T helper type 2 cytokines and thus favor a T helpertype 1 cell response in poultry.

Although individual countries differ in their approaches to training, examination and certification, there has been substantial progress toward establishing clinical immunology as a clinical subspecialty or as an area of special qualification.

Case studiesin immunology companion to immunology, Case studies in immunology Companion to Immunology, and more.

Vaccination has long been established as a preventative measure against infectious disease in both human and animal medicine and it is widely practiced in all farm animal species, including cattle.

This study characterized the alternative expression pattern of MALT1, A20, and NF-κB in patients with rheumatoid arthritis and suggested that CD39 expression was involved in iTreg generation and the enhanced suppressive ability of rapamycin induced Treg was partly due to Runx1 pathway.

Although individual countries differ in their approaches to training, examination and certification, there has been substantial progress toward establishing clinical immunology as a clinical subspecialty or as an area of special qualification.

The failure of the injected parent strain cells to respond to the antigen used may imply immunologic commitment of these cells, and the basis for the immunologic incompetence of the host with respect to T2 phage is presumed to be the attack of immunologically competent donor cells on the lymphoid cells of the recipient.

The goal of transplantation biologists is to take advantage of increased understanding of the serology of this locus in order to design new techniques for specifically modifying the immune response to MHC antigens and achieving specific tolerance.

A 20 kDa band of sheep HCF is an appropriate antigen for serodiagnosis of hydatid cyst infection and is effective for differential diagnosis of the infection.

How a thorough investigation of genomic variation relevant for individuals ’ variability in (auto)immune responses can contribute to the discovery of novel treatment approaches and drug targets, and yield predictive biomarkers to stratify cancer patient populations in precision and personalized medicine settings is discussed.

This chapter describes the processes contributing to CD4+ T cell decline and immune activation in untreated HIV infection and demonstrates knowledge of the effects of HIV on immune cells other than CD4- T cells.

The marginal headings and sub-headings have enabled the author to save much space and will enable the reader to follow the narrative as he would follow the successive developments in a story.

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Without a clear understanding of immunology, it is difficult to interpret the clinical rationale and consequences of blood transfusion as well as to interpret immunohaematological tests in the laboratory.

Since then, several important discoveries have launched a renaissance of research into the field of immunology, and many episodes based on the mechanisms of cause and effect were brilliantly documented.

You'll need to know your complement from your cytokines, but there's a lot more to clinical immunology than cutting edge science, says Scott Pereira.

The concept of forbidden foods that should not be eaten goes back to the Garden of Eden and apart from its religious meanings it may also have foreshadowed the concept of foods that can provoke adverse reactions, suggesting that allergic diseases have plagued mankind since the beginning of life on earth.

The immunologist of the month is Professor Takafira Mduluza, Senior Lecturer at the Biochemistry and Biotechnology Department at the University of Zimbabwe, who aims to characterize the induction and regulation of effector mechanisms of innate and acquired immunity to infecting agents, and how they promote parasite clearance without inducing immunopathology.

Investigation of physiological and pathological mechanisms of defence and specific response of the organisms against the presence of antigens, as microorganisms and toxins and students can address the inter-relation between pathogens and hosts from their knowledge acquired in cell biology, microbiology, biochemistry, genetics and animal biology.

The immune system functions are studied to understand allergic airway disease development as well as for selection of appropriate diagnostic and therapeutic options for patients with respiratory allergies.

It is concluded that maternal hyperthermia causes a marked increase in uterine activity, leading to fetal deterioration, and a metabolic acidosis developed in the mother and fetus and a profound hypoxia development in the fetus.

Overall the cumulative survival rate of patients with p53 expression was lower than that of the patients without expression and the prognostic value of p53 appears to be highly significant in surgically resected cases of squamous cell carcinoma.

The transcription factor determines B-cell lineage commitment by actively suppressing alternative lineage choices, so Pax5-deficient pro-B cells can take various differentiation pathways.

The present understanding of the possible roles of PP and LP in intestinal immunity in terms of induction, regulation, surveillance of immune responses and the antigen presenting cell types involved is reviewed.

The different clinical types of endemic cretinism are, in fact, manifestations of the same basic disorder (foetal bypothyroidism) phenotypically modified by the length and severity of postnatal hypothyroidistan.

It was found out that MHC peptide complex from thymus and kidney blocked the apoptosis in thymocytes, spleenocytes and blood lymphocytes which was induced by dexamethasone, calcium ionophor A23 187, i~-O-tetradecanoyl-i3-acetat and EDTA.

Four outstanding reviews are obtained that underscore the importance of colonization, immune function and gastrointestinal disease, and provide an excellent background for gastroenterologists to understand the pathophysiology of intestinal clinical disease states.

A review of the earlier chapters in this book documents the importance of immunological methods to the purification of proteins as well as to the identification of specific cDNA clones.

An editorial overview will allude to reports over the past 12 months that demonstrate the mechanisms by which bacterial components protect against inflammatory bowel disease (IBD) and allergy.

This chapter outlines the basic science and theory of immunology required for MRCP Part 1, before addressing the clinical aspects of Immunology for M RCP Part 2.

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