Top Research Papers on Nanoparticles

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This review will meticulously explore the current performance of polymeric nanoparticles against a myriad of diseases including cancer, viral and bacterial infections, before finally evaluating the advantages and crucial challenges that will determine their wider clinical potential in the decades to come.

In this review, the characteristics of nanoparticles that confers them with suitable and potentially toxic biological effects, as well as their applications in different biological fields and nanoparticle- based drugs and delivery systems in biomedicine including nano-based drugs currently approved by the U.S. Food and Drug Administration are discussed.

This review aims to establish factors affecting antibacterial and cytotoxic effects of silver nanoparticles, as well as to expose the advantages of using AgNPs as new antibacterial agents in combination with antibiotic, which will reduce the dosage needed and prevent secondary effects associated to both.

The research possibilities for these three lignocellulosic-derived nanoparticles are still wide and there is potential in drug delivery applications, especially for enhancing their characteristics with further surface modifications adjusted to the drugs.

Clinical applications of NPs should be revisited, and a deep understanding of the effects ofNPs from the pathophysiologic basis of a disease may bring more sophisticated diagnostic opportunities and yield more effective therapies and preventive features.

An overview of the beneficial and detrimental effects of NPs on stress response pathways with a focus on NP–protein interactions is provided and insights into the current knowledge of protein-based nanotoxicology are provided.

The combination of Ag nanomaterials and special nanostructures can significantly amplify the conversion of electromagnetic energy, especially in microwave absorption applications. Herein, a kind of...

The significance of nanoparticles (NPs) in technological advancements is due to their adaptable characteristics and enhanced performance over their parent material. They are frequently synthesized by reducing metal ions into uncharged nanoparticles using hazardous reducing agents. However, there have been several initiatives in recent years to create green technology that uses natural resources instead of dangerous chemicals to produce nanoparticles. In green synthesis, biological methods are used for the synthesis of NPs because biological methods are eco-friendly, clean, safe, cost-effective...

This review aimed to present the most commonly used nanoparticles for cancer applications, offering alternative therapeutic strategies and improving outcomes for many cancer treatments.

The present review aims to highlight the potential of silver and gold NPs as innovative and effective therapeutics in the field of biomedicine, citing some of their most relevant current applications.

The different nanolignin preparation methods are summarized, emphasizing anti-solvent precipitation, self-assembly and interfacial crosslinking, and advances in numerous potential high-value applications, such as use in food packaging, biomedical, chemical engineering and biorefineries are described.

Understanding the interactions between amines and the surface of gold nanoparticles is important because of their role in the stabilization of the nanosystems, in the formation of the protein corona, and in the preparation of semisynthetic nanozymes. By using fluorescence spectroscopy, electrochemistry, X‐ray photoelectron spectroscopy, high‐resolution transmission electron microscopy, and molecular simulation, a detailed picture of these interactions is obtained. Herein, it is shown that amines interact with surface Au(0) atoms of the nanoparticles with their lone electron pair with a strengt...

The NTA method demonstrated the ability to discriminate between the behaviors of LNPs according to serum proteins’ interactions, and CSL3 lipid and Cer-PEG were confirmed to have promise for LNP formulation.

This review explores and discusses the opportunities, challenges, and limitations that UCNPs exhibit as bioimaging probes and highlights applications with spatial dimensions ranging from the single nanoparticle level to cellular, tissue, and whole animal imaging.

A critical review of recent progress in microfluidic NPs for drug delivery with a focus on the synthesis of organic NPs usingmicrofluidics and their applications in making popular and clinically relevant NPs.

Nanoparticles are defined as particulate dispersions or solid particles with a size between 10 and 1000 nm. A one billionth of a metre scale is the simplest unit of measurement for nanotechnology. Silver nanoparticles superiority over silver in bulk forms is primarily due to the size, shape, composition, crystallinity, and structure of AgNPs. Silver nanoparticles synthesis can be achieved by physical, chemical and green methods. Evaporation-condensation and laser ablation processes are used in the physical synthesis of silver nanoparticle. Evaporation-condensation has been used to create a num...

Nanoparticle–nanoparticle (NP–NP) interactions were studied by choosing oppositely charged colloidal suspensions of Au and Ag NPs. For this purpose, sodium dodecyl sulfate-stabilized Au NPs were ti...

Copper nanoparticles, in particular, are being utilized as antimicrobial agents as well as their interaction with other particles helps to improve the antimicrobial efficacy.

Current challenges in drug delivery warrant future studies about structure-function correlations, large-scale production, and targeted delivery to realize the full potential of lipid nanoparticles for wider clinical and pharmaceutical applications in future.

An overview of the construction strategies and application advances of multifunctional nanoparticles is provided, which emphasized on the functionalization and modification strategies, which provide additional functions to the nanoparticle.

The main focus of this research is on the various pathways that SLNs use to enter cells and penetrate skin, including numerous formulation and dosage form parameters that may affect SLN absorption via the skin.

Oxide micro- and nanoparticles are ubiquitous in the natural environment. They have long been used as catalysts, but have found novel applications with the advent of nanotechnologies. From a fundamental point of view, they bridge the gap between the properties of isolated atoms or molecules and those of bulk condensed phases. They present a large spectrum of atomic and electronic structures, due to their finite size in the three dimensions of space and the fact that their atoms are nearly all surface atoms. They represent the first stages of nucleation and growth of larger size oxides, and the...

The use of commercial Sonazoid microbubbles leads to significantly lower uptake than when using nanoparticle-loaded microbubbling, suggesting that proximity between cells, nanoparticles and microbubble is important, and that mainly nanoparticles in the shell are taken up, rather than free nanoparticle in solution.

This review concentrated mostly on the classification of nanoparticles, the technique of synthesis, the evaluation of nanop particles, and the list of FDA-approved nanomedicines now available on the market.

The development and application of trimetallic nanoparticles continues to accelerate rapidly as a result of advances in materials design, synthetic control, and reaction characterization. Following the technological successes of multicomponent materials in automotive exhausts and photovoltaics, synergistic effects are now accessible through the careful preparation of multielement particles, presenting exciting opportunities in the field of catalysis. In this review, we explore the methods currently used in the design, synthesis, analysis, and application of trimetallic nanoparticles across bot...

The proposed SNC dynamics-based method holds great potential for developing reliable electrochemical approaches to evaluate NP sizes accurately and showed that the current lifetime increased with NP size.

Two silver nanoparticles containing compounds were prepared by simple chemical reactions and characterized by X-ray diffraction (XRD), infra-red spectrum (FTIR) and atomic force microscope (AFM). These functionalized silver nanoparticles were used to study their biological activity against four types of fungi. These compounds proved to have high inhibition effect against all types of studied fungi. Due to the presence of silver nanoparticles which increases nystatin and clotrimazol interact with the fungi.

This work presents a method to analyze particle size and aggregation in blood plasma using a commercially available nanoparticle tracking analysis (NTA) system and finds that PEGylation of the particles is found to decrease the multicomponent aggregation.

Catalysis holds a significant position in the field of chemistry, wherein it manifests in three distinct directions that exhibit minimal overlap: heterogeneous, enzymatic, and homogeneous. Heterogeneous and homogeneous catalysis are recognized as distinct fields championed by two scientific societies, namely solid state and molecular chemistry. Despite their differences, both domains share a common goal of seeking to enhance catalytic performance. Nanocatalysis has gained prominence as a burgeoning scientific discipline in recent times, owing to its exceptional levels of activity, selectivity,...

The definition of nanopesticides, the types of nanoparticles used in agriculture and their specific synergistic mechanisms are introduced, their safety is evaluated, and their future application prospects are examined.

The barriers encountered in nanoparticle delivery to plants are highlighted, emphasizing the need for innovative approaches to optimize transport efficiency and the reliance on multiple detection methods for data validation is emphasized to enhance the reliability of the research findings.

This review describes how the optical properties of AuNPs have been exploited for the design of plasmonic biosensors that only require the simple mixing of reagents combined with a visual readout and focuses on the molecular mechanisms involved.

Luminescence thermometry has emerged as a very versatile optical technique for remote temperature measurements, exhibiting a wide range of applicability spanning from cryogenic temperatures to 2000 K. This technology has found extensive utilization across many disciplines. In the last thirty years, there has been significant growth in the field of luminous thermometry. This growth has been accompanied by the development of temperature read-out procedures, the creation of luminescent materials for very sensitive temperature probes, and advancements in theoretical understanding. This review arti...

A fully analytical model that requires only a few experimental configurations to determine the ideal UCNP-FRET system within a few minutes is developed and demonstrated the powerful feat of combining a few selected experiments with sophisticated but rapid modeling to accomplish an ideal FRET biosensor.

Multicomponent nanoparticle superlattices (SLs) promise the integration of nanoparticles (NPs) with remarkable electronic, magnetic, and optical properties into a single structure. Here, we demonstrate that heterodimers consisting of two conjoined NPs can self-assemble into novel multicomponent SLs with a high degree of alignment between the atomic lattices of individual NPs, which has been theorized to lead to a wide variety of remarkable properties. Specifically, by using simulations and experiments, we show that heterodimers composed of larger Fe3O4 domains decorated with a Pt domain at one...

5 principles to consider when designing nanoparticles for cancer targeting are presented and their application for engineering nanoparticle delivery systems to carry therapeutics to tumors or other disease targets are described.

An overview of copper nanoparticles and their applications in dentistry is provided to enhance the physical and chemical properties of various dental materials, such as dental amalgam, restorative cements, adhesives, resins, endodontic-irrigation solutions, obturation materials, dental implants, and orthodontics archwires and brackets.

Recent advances of nanoparticles in the development of next-generation vaccines against influenza viruses, coronaviruses, HIV, hepatitis viruses, and many others are reviewed, including applications of self-assembling protein polymers, virus-like particles, nano-carriers, and nano-adjuvants in antiviral vaccines.

The core features of LNPs for RNA delivery are discussed and the perspective on the future of RNA therapies and some questions that remain in the realm of LNP formulation and optimization are offered.

As nanoparticles used in biomedicine become increasingly prevalent and biochemically complex, the field of protein corona research will need to focus on developing analytical approaches and characterization techniques appropriate for each unique nanoparticle formulation.

The use of nanomaterials in food production requires compliance with all legal requirements regarding the safety and quantity of nano-processed food products described in this review.

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Colloidal gold nanoparticles (AuNPs) have myriad scientific and technological applications, but their fundamental redox chemistry is underexplored. Reported here are titration studies of oxidation and reduction reactions of aqueous AuNP colloids, which show that the AuNPs bind substantial hydrogen (electrons + protons) under mild conditions. The 5 nm AuNPs are reduced to a similar extent with reductants from borohydrides to H2 and are reoxidized back essentially to their original state by oxidants, including O2. The reactions were monitored via surface plasmon resonance (SPR) optical absorptio...

Rapidly increasing industrialisation has human needs, but the consequences have added to the environmental harm. The pollution caused by several industries, including the dye industries, generates a large volume of wastewater containing dyes and hazardous chemicals that drains industrial effluents. The growing demand for readily available water, as well as the problem of polluted organic waste in reservoirs and streams, is a critical challenge for proper and sustainable development. Remediation has resulted in the need for an appropriate alternative to clear up the implications. Nanotechnology...

The pseudo-two-dimensional (2D) morphology of plate-like metal nanoparticles makes them one of the most anisotropic, mechanistically understood, and tunable structures available. Although well-known for their superior plasmonic properties, recent progress in the 2D growth of various other materials has led to an increasingly diverse family of plate-like metal nanoparticles, giving rise to numerous appealing properties and applications. In this review, we summarize recent progress on the solution-phase growth of colloidal plate-like metal nanoparticles, including plasmonic and other metals, wit...

Nanoparticle (NP)-based advanced drug delivery systems can enable the controlled release of therapeutic reagents and the delivery of therapeutics into specific cell types, thereby benefiting bone regeneration through osteoimmunomodulation.

This review enumerates various types of nanoparticles that have entered clinical trials for cancer treatment and the obstacles in the journey of nanodrug from clinic to market.

This study is focused on hydrothermal synthesis method of zinc oxide nanoparticles by usingammonia and zinc chloride. Synthesized nanoparticles have been characterized by using Xray Diffraction, UV-vis and Photon Cross Correlation (PCCS) spectroscopies, TEManalysis. ZnO thin films were prepared by spin coating method from the solution of ZnOnanoparticles. XRD peak corresponds to hexagonal structure with cell parameter a=0.326nm and c=0.522 nm. The grain size of zinc oxide nanoparticles has been determined 43.3nm using the Scherrer formula. As a result of PCCS measurement, synthesized zinc oxid...

Ag and Au nanoparticles (NPs) were used as color indicators to determine the monomer/micelle adsorption on the NP surface. A simple methodology based on the color change of Ag/Au NPs upon interacting with surface-active molecules was developed. A contrasting color change occurred when NPs interact with the monomer/micelle. This was demonstrated by monitoring the adsorption behavior of a series of Gemini surfactants. UV-visible measurements showed a large change in the intensity and wavelength of Ag/Au NP absorbance upon the surface adsorption of the monomer/micelle of Gemini surfactants. The m...