Top Research Papers on Nutraceuticals
Dive into the top research papers on Nutraceuticals and uncover groundbreaking studies that highlight the health benefits and applications of functional foods. Enhance your understanding of this innovative field with these authoritative sources.
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Nutraceuticals in Neurological Disorders
168 Citations 2020Rashita Makkar, Tapan Behl, Simona Bungău + 8 more
International Journal of Molecular Sciences
An association between food habits and the individual lifestyle with neurodegeneration has been manifested, thereby proposing the role of nutraceuticals as prophylactic treatment for neurological interventions.
Functional Foods and Nutraceuticals
145 Citations 2020Chukwuebuka Egbuna, Genevieve D. Tupas
journal unavailable
This book discusses and explains important bio-active components in specific groups of functional foods and/or nutraceuticals that are responsible for the health benefits they offer. It details the different formulations of functional foods and nutraceutical products.
Nuts: Natural Pleiotropic Nutraceuticals
112 Citations 2021Emilio Ros, Annapoorna Singh, James H. O’Keefe
Nutrients
As they are rich in salutary bioactive compounds and beneficially impact various health outcomes, nuts can be considered natural pleiotropic nutraceuticals.
The biology of ergothioneine, an antioxidant nutraceutical
246 Citations 2020Irina Borodina, Louise C. Kenny, Cathal McCarthy + 5 more
Nutrition Research Reviews
Mushroom or ERG consumption seems to provide significant prevention against oxidative stress in a large variety of systems, and it may have value as a nutraceutical and antioxidant more generally.
The current use and evolving landscape of nutraceuticals
196 Citations 2021Avijeet Chopra, Ronan Lordan, Olaf K. Horbańczuk + 9 more
Pharmacological Research
An understanding of the key drivers of the nutr pharmaceutical market alongside a consistent and well-defined regulatory framework will provide further opportunities for growth, expansion, and segmentation of nutraceuticals applications.
Nutraceuticals and Cancer: Potential for Natural Polyphenols
135 Citations 2021Jessica Maiuolo, Micaela Gliozzi, Cristina Carresi + 13 more
Nutrients
This review aims to discuss the current literature on four natural bioactive extracts mostly characterized by a specific polyphenolic profile, and reports that natural antioxidants may contribute to improving the compliance of patients undergoing anticancer treatment.
Paraprobiotics: A New Perspective for Functional Foods and Nutraceuticals
192 Citations 2021Rosa Anna Siciliano, Anna Reale, Maria Fiorella Mazzeo + 3 more
Nutrients
This review provides an overview of central issues on paraprobiotics and highlights the urgent need for further studies aimed at assessing safety and efficacy of these products and their mechanisms of action in order to support decisions of regulatory authorities.
Nutraceutical characteristics of the brown seaweed carotenoid fucoxanthin
112 Citations 2020Kazuo Miyashita, Fumiaki Beppu, Masashi Hosokawa + 2 more
Archives of Biochemistry and Biophysics
Anti-obesity effect of Fx is the most well-studied and most promising effect and is primarily based on the upregulation of thermogenesis by uncoupling protein 1 expression and the increase in the metabolic rate induced by mitochondrial activation.
Potential Food and Nutraceutical Applications of Alginate: A Review
119 Citations 2022Decheng Bi, Xu Yang, Lijun Yao + 4 more
Marine Drugs
This review comprehensively covers the analysis ofAlginate and discussed the potential applications of alginate in the food industry and nutraceuticals.
Safety of Probiotics: Functional Fruit Beverages and Nutraceuticals
122 Citations 2020Irena Žuntar, Zvonimir Petrić, Danijela Bursać Kovačević + 1 more
Foods
This reviews aims to give an evidence-based perspective of probiotic safety, focusing on probiotic fruit beverages and nutraceuticals, by providing documented clinical case reports and studies.
A review on the influence of nutraceuticals and functional foods on health
130 Citations 2024Arumugam Vignesh, Thomas Cheeran Amal, Ariyan Sarvalingam + 1 more
Food Chemistry Advances
In recent years, functional foods have gained attention for their potential health benefits beyond basic nutrition, serving as rich sources of proteins, carbohydrates, vitamins, and dietary fiber. Enriched with bioactive compounds such as polyphenols, tannins, flavonoids, and alkaloids, these foods have shown promise in inhibiting cell signaling pathways related to proliferation, communication, and apoptosis. Key components in functional foods offer health benefits. Omega-3 fatty acids scavenge free radicals, reducing the risk of chronic diseases like heart disease and cancer. Antioxidants in ...
Nutraceuticals in the Management of Dyslipidemia: Which, When, and for Whom? Could Nutraceuticals Help Low-Risk Individuals with Non-optimal Lipid Levels?
105 Citations 2021Arrigo F.G. Cicero, Federica Fogacci, Anca Pantea Stoian + 5 more
Current Atherosclerosis Reports
Current evidence suggests that some clinically tested lipid-lowering nutraceuticals could be safely used to improve plasma lipid levels in subjects affected by mild-to-moderate dyslipidaemia with low cardiovascular risk.
Encapsulation of probiotics and nutraceuticals: Applications in functional food industry
291 Citations 2021Priscilla Magro Reque, Adriano Brandelli
Trends in Food Science & Technology
The current relevance of functional foods in human health and well-being has led to an increased interest in developing new types of oral administration systems for probiotics and nutraceuticals. Encapsulation may provide protection and sustained delivery in food formulations. The recent discussions about probiotics encapsulation for application in both nutraceutical and food sectors are addressed. The topics approached include encapsulation systems, nutraceuticals and probiotics concepts and current market situation, microbial microencapsulation, and food applications for beyond their use in ...
Nutraceutical role of selenium nanoparticles in poultry nutrition: a review
106 Citations 2020Fazul Nabi, Muhammad Asif Arain, Faiz‐ul Hassan + 7 more
World s Poultry Science Journal
SUMMARYSelenium (Se) is an essential trace element with diverse physiological functions related to cellular homoeostasis, body metabolism and antioxidant defence. Se is an integral constituent of at least 25 selenoproteins in the body that regulate cellular redox and antioxidant defence enzymes systems control free radicles of reactive oxygen species . Dietary Se plays key role in immunity, growth and fertility in chickens, which require optimum levels in their diets to maintain high reproductive and productive performance of birds. In the last decade, dietary supplementation with selenium nan...
Food flavonols: Nutraceuticals with complex health benefits and functionalities
166 Citations 2021Davide Barreca, Domenico Trombetta, Antonella Smeriglio + 5 more
Trends in Food Science & Technology
Flavonols are one of the most promising class of bioactive compounds belonging to the broad family of the flavonoids, characterized by a unique set of features in their basic chemical skeleton and several specific substitutions in selected position of the rings A, B and C. This interesting class of phytochemicals includes compounds such as quercetin, kaempferol, myricetin, rhamnetin, morin, fisetin, galagin, azaleatin and their respective glycosyl derivatives. They have been identified in several foods and provide them great health benefits. This review updates and integrates, in a critical fa...
A Comprehensive Review on Nutraceuticals: Therapy Support and Formulation Challenges
262 Citations 2022Vivek Puri, Manju Nagpal, Inderbir Singh + 6 more
Nutrients
The latest key findings that show the therapeutic action of nutraceutical’s bioactive molecules on various diseases have also been discussed and confirmed the exponential growth ofNutraceuticals’ market value.
Recent Advances in Marine-Based Nutraceuticals and Their Health Benefits
128 Citations 2020Vida Šimat, Nariman Elabed, Piotr Kulawik + 6 more
Marine Drugs
The oceans have been the Earth’s most valuable source of food. They have now also become a valuable and versatile source of bioactive compounds. The significance of marine organisms as a natural source of new substances that may contribute to the food sector and the overall health of humans are expanding. This review is an update on the recent studies of functional seafood compounds (chitin and chitosan, pigments from algae, fish lipids and omega-3 fatty acids, essential amino acids and bioactive proteins/peptides, polysaccharides, phenolic compounds, and minerals) focusing on their potential ...
Lipid Nanoparticles: An Effective Tool to Improve the Bioavailability of Nutraceuticals
120 Citations 2023Rabia Ashfaq, Akhtar Rasul, Sajid Asghar + 3 more
International Journal of Molecular Sciences
The primary objective of this work is to explore the synergy between nature and nanotechnology, encompassing a wide range of research aimed at encapsulating natural therapeutic molecules within LNPs.
Functional and Nutraceutical Significance of Amla (Phyllanthus emblica L.): A Review
131 Citations 2022Maryam Gul, Zhiwei Liu, Iahtisham Ul‐Haq + 8 more
Antioxidants
The nutritional aspects, rich phytochemistry and health-promoting effects of amla, a tree native to the India and Southeast Asia regions that produces fruits rich in bioactive compounds, are highlighted.
A Comprehensive Review of the Nutraceutical and Therapeutic Applications of Red Seaweeds (Rhodophyta)
186 Citations 2020João Cotas, Adriana Leandro, Diana Pacheco + 2 more
Life
The red seaweed group (Rhodophyta) is one of the phyla of macroalgae, among the groups Phaeophyceae and Chlorophyta, brown and green seaweeds, respectively, which have exceptional properties with nutraceutical, pharmacological, and biomedical interest.
Encapsulation of Pharmaceutical and Nutraceutical Active Ingredients Using Electrospinning Processes
101 Citations 2021Mina Zare, Karolina Dziemidowicz, Gareth R. Williams + 1 more
Nanomaterials
This review aims to briefly discuss the concept of electrospinning and recent progress in manufacturing electrospun drug delivery systems, and will further consider in detail the encapsulation of nutraceuticals, particularly probiotics.
Bioactive Peptides as Potential Nutraceuticals for Diabetes Therapy: A Comprehensive Review
121 Citations 2021Priya Antony, Ranjit Vijayan
International Journal of Molecular Sciences
The focus is on the effectiveness of food-derived bioactive peptides possessing antidiabetic activity as evidenced by in vitro and in vivo studies and the future prospects of peptide-based drugs for the treatment of diabetes.
An update on β-sitosterol: A potential herbal nutraceutical for diabetic management
622 Citations 2020Shyamaladevi Babu, Selvaraj Jayaraman
Biomedicine & Pharmacotherapy
The experimental studies on SIT gives a clear evidence that the potential phytosterol can be used as supplements to fight against life threatening diseases.
Role of nutraceuticals during the transition period of dairy cows: a review
116 Citations 2020Vincenzo Lopreiato, Matteo Mezzetti, Luca Cattaneo + 3 more
Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology
Abstract The transition period of dairy cattle is characterized by a number of metabolic, endocrine, physiologic, and immune adaptations, including the occurrence of negative energy balance, hypocalcemia, liver dysfunction, overt systemic inflammatory response, and oxidative stress status. The degree and length of time during which these systems remain out of balance could render cows more susceptible to disease, poor reproductive outcomes, and less efficient for milk production and quality. Studies on both monogastrics and ruminants have reported the health benefits of nutraceuticals (e.g. pr...
Nanoliposomes and Tocosomes as Multifunctional Nanocarriers for the Encapsulation of Nutraceutical and Dietary Molecules
110 Citations 2020Ali Zarrabi, Mandana Alipoor Amro Abadi, Sepideh Khorasani + 6 more
Molecules
Various aspects of nanoliposomes, in comparison with tocosomes, are reviewed, including the ingredients used in their manufacture, formation mechanisms and issues pertaining to their application in the formulation of health promoting dietary supplements and functional food products.
Macrofungi as a Nutraceutical Source: Promising Bioactive Compounds and Market Value
185 Citations 2021Allen Grace T. Niego, Sylvie Rapior, Naritsada Thongklang + 4 more
Journal of Fungi
The converging trends and popularity of eastern herbal medicines, natural/organic food product preference, gut-healthy products, and positive outlook towards sports nutrition are supporting the growth in the medicinal mushroom market.
Encapsulation of food bioactives and nutraceuticals by various chitosan-based nanocarriers
199 Citations 2020Safoura Akbari‐Alavijeh, Rezvan Shaddel, Seid Mahdi Jafari
Food Hydrocolloids
In this review, various approaches and techniques for development of chitosan-based nanodelivery systems with an overview of the related studies will be discussed, and nutritional and functional properties of the nanostructures and relevant safety issues are highlighted.
Microalgal Cell Biofactory—Therapeutic, Nutraceutical and Functional Food Applications
117 Citations 2021Boda Ravi Kiran, S. Venkata Mohan
Plants
A detailed overview of the key algal metabolites, which plays a crucial role in nutraceutical, functional foods, and animal/aquaculture feed industries are provided.
Sustainable production of pharmaceutical, nutraceutical and bioactive compounds from biomass and waste
183 Citations 2021Claudia Espro, Emilia Paone, Francesco Mauriello + 5 more
Chemical Society Reviews
The aim of this tutorial review is to provide a general overview of processes, technologies and challenges in the production of pharmaceutical and bioactive compounds from food waste and lignocellulosic residues.
Plant-Derived Nutraceuticals and Immune System Modulation: An Evidence-Based Overview
117 Citations 2020Antonella Di Sotto, Annabella Vitalone, Silvia Di Giacomo
Vaccines
The up to date knowledge about the immunomodulating properties of polysaccharides, fatty acids and labdane diterpenes have been analyzed, in order to give scientific basic and clinical evidence to support their practical use.
Food hydrocolloids: Functional, nutraceutical and novel applications for delivery of bioactive compounds
131 Citations 2020Mehnaza Manzoor, Jagmohan Singh, Julie D Bandral + 2 more
International Journal of Biological Macromolecules
Based on prevailing literature hydrocolloids offer significant opportunities in tailoring the nutritional value along with providing health benefits via controlling gastric emptying and ileal brake mechanism, lowering plasma cholesterol levels, glycemic response, postprandial glucose and insulin levels, and prevention of colon cancer.
Potential role of important nutraceuticals in poultry performance and health - A comprehensive review
127 Citations 2021Mahmoud Alagawany, Shaaban S. Elnesr, Mayada R. Farag + 13 more
Research in Veterinary Science
The summary of various bioactive ingredients that act as nutraceuticals and their mode of action in growth promotion and elevation of the immune system has been presented.
Molecular docking as a tool for the discovery of molecular targets of nutraceuticals in diseases management
915 Citations 2023Peter Chinedu Agu, Celestine Azubuike Afiukwa, O.U. Orji + 5 more
Scientific Reports
This review explored molecular docking's application to the study of dietary supplements and disease management and highlighted biochemistry pathways and models from recent studies that have revealed molecular mechanisms to pinpoint new nutraceuticals' effects on disease pathogenesis.
Natural therapeutics and nutraceuticals for lung diseases: Traditional significance, phytochemistry, and pharmacology
155 Citations 2022Md. Mominur Rahman, Shabana Bibi, Md. Saidur Rahaman + 18 more
Biomedicine & Pharmacotherapy
The results of the mentioned natural metabolites repurposed for different lung diseases especially for SARS-CoV-2 should be evaluated more by advance computational applications, experimental models in the biological system, also need to be validated by clinical trials so that they may be able to retrieve potential drugs for most challenging lung diseases, especially Sars-Cov-2.
Dietary Supplements and Nutraceuticals under Investigation for COVID-19 Prevention and Treatment
122 Citations 2021Ronan Lordan, Halie M. Rando, Casey S. Greene
mSystems
Sales of dietary supplements and nutraceuticals have increased during the pandemic due to their perceived “immune-boosting” effects. However, little is known about the efficacy of these dietary supplements and nutraceuticals against the novel coronavirus (severe acute respiratory syndrome coronavirus 2 [SARS-CoV-2]) or the disease that it causes, CoV disease 2019 (COVID-19).
Therapeutic values and nutraceutical properties of shiitake mushroom (Lentinula edodes): A review
137 Citations 2023Ishtiaq Ahmad, Maryum Arif, Mimi Xu + 3 more
Trends in Food Science & Technology
Mushrooms are generally regarded as useful products with multiple applications in the food and health industry. Shiitake (Lentinula edodes) is one of the most cultured and consumed mushrooms around the world. With more complexity in medical science and phenomenon like antibiotic resistance, have led to the search for alternatives for disease treatment and prevention. Shiitake mushroom is nutritionally rich and contains numerous minerals (Potassium, Manganese, Magnesium, Iron, and Phosphorus) and vitamins (pro-vitamin D2, vitamin B1, B2, B6, B12, and niacin) which make it a potential source of ...
Nutraceuticals: Transformation of Conventional Foods into Health Promoters/Disease Preventers and Safety Considerations
222 Citations 2021Mudhi AlAli, Maream Alqubaisy, Mariam Nasser Aljaafari + 6 more
Molecules
Different classifications of nutraceuticals and their potential therapeutic activity, such as anti-cancer, antioxidant, anti-inflammatory and anti-lipid activity in disease will be reviewed.
Microalgae for high-value products: A way towards green nutraceutical and pharmaceutical compounds
259 Citations 2021Sanjeet Mehariya, Rahul Kumar Goswami, Obulisamy Parthiba Karthikeysan + 1 more
Chemosphere
This review will provide the concept of microalgal biorefinery to produce bioactive compounds at industrial scale platform for their application in the nutraceutical and pharmaceutical sector considering their current and future market trends.
Food and nutraceutical functions of sesame oil: An underutilized crop for nutritional and health benefits
110 Citations 2022Sapna Langyan, Pranjal Yadava, Sanjula Sharma + 5 more
Food Chemistry
Sesame is the oldest oilseed crop known to humanity, though it contributes a small share in the global vegetable oil production. Sesame oil contains nutrients, including lignans, tocopherols, phytosterols, natural antioxidants, and bioactive compounds. It provides various health benefits such as anti-lipogenic, hypo-cholesterolemic, anti-degenerative, and neural health-promoting properties. Being an under-utilized minor crop, it has not received enough research attention for its food and nutraceutical potential. The sesame crop is a potential candidate to maintain the diversity of food oils an...
Polyphenols as Plant-Based Nutraceuticals: Health Effects, Encapsulation, Nano-Delivery, and Application
211 Citations 2022Zhiheng Zhang, Xiaojing Li, Shangyuan Sang + 6 more
Foods
The health benefits of plant polyphenols in the prevention of various diseases are summarized, with a review of the research progress into bio-based nanocarriers for the improvement of the oral bioavailability of polyphenolic compounds.