Discover the most influential research papers on Rheumatoid Arthritis. This collection highlights significant studies and advancements in understanding, diagnosing, and treating this chronic condition. Dive into the insights from top researchers and stay updated on critical developments.
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Wu Jing, L. Qiang, J. Deng + 2 more
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In vitro experiments confirmed that IL‐33 also exerted a U‐type dose‐dependent regulatory effect on FLS function, and the applicability of this mathematical model in clinical practice is limited.
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On the last two decades several studies showed an increased prevalence of coronary and stroke disease and also the cardiovascular disease represents the principal mortality cause in RA patients; in both male and female subjects.
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Rheumatoid arthritis (RA) is a systemic inflammatory autoimmune disease that is characterized by a debilitating chronic, symmetric polyarthritis with significant extra-articular manifestations, which include rheumatoid nodules, pyoderma gangrenosum, granulomatous dermatitis, vasculitis, and internal organ involvement. The disease process is often progressive, resulting in limitation of joint function. Ultimately there may be a resultant decline in functional status, possibly leading to premature death. Permanent remission is unusual.
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Rheumatoid arthritis (RA) is a systemic inflammatory autoimmune disease that is characterized by a debilitating chronic, symmetric polyarthritis with significant extra-articular manifestations, which include rheumatoid nodules, pyoderma gangrenosum, granulomatous dermatitis, vasculitis, and internal organ involvement. The disease process is often progressive, resulting in limitation of joint function. Ultimately there may be a resultant decline in functional status, possibly leading to premature death. Permanent remission is unusual.
authors unavailable
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Rheumatoid arthritis (RA) is a systemic inflammatory autoimmune disease that is characterized by a debilitating chronic, symmetric polyarthritis with significant extra-articular manifestations, which include rheumatoid nodules, pyoderma gangrenosum, granulomatous dermatitis, vasculitis, and internal organ involvement. The disease process is often progressive, resulting in limitation of joint function. Ultimately there may be a resultant decline in functional status, possibly leading to premature death. Permanent remission is unusual.
authors unavailable
journal unavailable
Rheumatoid arthritis (RA) is a systemic inflammatory autoimmune disease that is characterized by a debilitating chronic, symmetric polyarthritis with significant extra-articular manifestations, which include rheumatoid nodules, pyoderma gangrenosum, granulomatous dermatitis, vasculitis, and internal organ involvement. The disease process is often progressive, resulting in limitation of joint function. Ultimately there may be a resultant decline in functional status, possibly leading to premature death. Permanent remission is unusual.
authors unavailable
journal unavailable
Rheumatoid arthritis (RA) is a systemic inflammatory autoimmune disease that is characterized by a debilitating chronic, symmetric polyarthritis with significant extra-articular manifestations, which include rheumatoid nodules, pyoderma gangrenosum, granulomatous dermatitis, vasculitis, and internal organ involvement. The disease process is often progressive, resulting in limitation of joint function. Ultimately there may be a resultant decline in functional status, possibly leading to premature death. Permanent remission is unusual.
authors unavailable
journal unavailable
Rheumatoid arthritis (RA) is a systemic inflammatory autoimmune disease that is characterized by a debilitating chronic, symmetric polyarthritis with significant extra-articular manifestations, which include rheumatoid nodules, pyoderma gangrenosum, granulomatous dermatitis, vasculitis, and internal organ involvement. The disease process is often progressive, resulting in limitation of joint function. Ultimately there may be a resultant decline in functional status, possibly leading to premature death. Permanent remission is unusual.
authors unavailable
journal unavailable
Rheumatoid arthritis (RA) is a systemic inflammatory autoimmune disease that is characterized by a debilitating chronic, symmetric polyarthritis with significant extra-articular manifestations, which include rheumatoid nodules, pyoderma gangrenosum, granulomatous dermatitis, vasculitis, and internal organ involvement. The disease process is often progressive, resulting in limitation of joint function. Ultimately there may be a resultant decline in functional status, possibly leading to premature death. Permanent remission is unusual.
authors unavailable
journal unavailable
Rheumatoid arthritis (RA) is a systemic inflammatory autoimmune disease that is characterized by a debilitating chronic, symmetric polyarthritis with significant extra-articular manifestations, which include rheumatoid nodules, pyoderma gangrenosum, granulomatous dermatitis, vasculitis, and internal organ involvement. The disease process is often progressive, resulting in limitation of joint function. Ultimately there may be a resultant decline in functional status, possibly leading to premature death. Permanent remission is unusual.
authors unavailable
journal unavailable
Rheumatoid arthritis is a systemic inflammatory autoimmune disease that is characterized by a debilitating chronic, symmetric polyarthritis with significant extra-articular manifestations, which include rheumatoids nodules, pyoderma gangrenosum, granulomatous dermatitis, vasculitis, and internal organ involvement.
authors unavailable
journal unavailable
Rheumatoid arthritis (RA) is a systemic inflammatory autoimmune disease that is characterized by a debilitating chronic, symmetric polyarthritis with significant extra-articular manifestations, which include rheumatoid nodules, pyoderma gangrenosum, granulomatous dermatitis, vasculitis, and internal organ involvement. The disease process is often progressive, resulting in limitation of joint function. Ultimately there may be a resultant decline in functional status, possibly leading to premature death. Permanent remission is unusual.
A. Gcelu, A. Kalla
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The initial aim should be to differentiate features of early RA from other diseases with similar presentations, such as psoriatic arthritis (PsA) or systemic lupus erythematosus (SLE) and from those that will remit spontaneously.
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The aim of this study is to evaluate the role of vitamin D in the pathogenesis of early RA, and to test if T cells from RA patients are equally responsive to vitamin D as respect to healthy age and sex matched controls.
This study showed that the model was able to recapitulate certain pathological features of an RA cartilage, and has a great potential to be used for screening new therapeutic drugs/strategies, thereby contribut-ing to the improvement of anti-rheumatic treatment.
Hiroshi Funabashi, H. Ishikawa, S. Kaise + 7 more
Japanese Journal of Clinical Immunology
症例48歳男性. 1981年多発関節炎, 1983年上下肢筋痛・筋萎縮・歩行不能. 1984年上下肢しびれ感,食欲不振出現.同年2月当科入院す.入院時検査成績で赤沈亢進, CRP 6 (+), RF陽性, IC高値,左大腿皮膚生検でのPN型血管炎よりMRAと診断された.プレドニソロンにて加療中3月27日free air出現し,緊急手術施行.回腸に4個の潰瘍穿孔を認めた.術後順調に経過していたが,術後60日目に腹痛再発し,両側肺炎による呼吸不全のため6月24日永眠した.病理解剖にて回腸・空腸の多発潰瘍,直腸穿孔,肺カンジダ症を認めた.また,病期により血管炎組織所見に変化がみられ(生検時PN型,手術時PN型, RA型, EA型,剖検時EA型),ステロイド剤による影響が示唆された.
F. Reyes, S. Saavedra, K. Vergara + 2 more
European Respiratory Journal
In this cohort, the diagnosis of ILD was made in the context of an established disease, presenting the majority radiological pattern of UIP, and the factors associated with poor lung function forced smoking and the duration of RA and the use of LEF stand out as a protective factor.
J. Calvo Alén, C. Baamonde, E. Aurrecoechea + 2 more
Annals of the Rheumatic Diseases
RA patients present diverse alterations of lipid and lipoprotein metabolism, which may confer them a CV risk profile, which might be due to the competitive action for HDL of the inflammatory molecules, such as SAA, which could render functionally inactive the most part of this enzyme.
P. Peichl, G. Haberhauer, M. Scriba + 1 more
International Journal of Immunopathology and Pharmacology
Evidence of the specific binding capacity of RF to the virus antigen in chronic CMV infection as well as their defined binding capacity to the Fc Fragment of IgG suggest CMV specific RF as the pathogenetic factor of malignant forms of inflammatory rheumatism.
Ahalya R. Kesavapillai, S. Aslam, S. Umapathy + 1 more
Diagnostics
Depending on the performance measures, the RA-XTNet model can be used as an effective automated diagnostic method to diagnose RA accurately and rapidly in hand radiographs and thermal images.