Top Research Papers on Sleep

Overall, findings suggest that sleep-wake disorders lead to pronounced alterations in specific metabolic pathways, which might contribute to the association of sleep disorders with other psychiatric disorders and medical conditions.

Recommendations to improve sleep include achieving 7 to 9 h of sleep, maintaining a consistent sleep/wake schedule, a regular bedtime routine, engaging in regular exercise, and adopting a contemplative practice to promote better quality and duration of sleep.

An at-home portable system that includes wireless sleep sensors and wearable electronics with embedded machine learning and deep learning offers automated sleep scoring, demonstrating portability, and point-of-care usability is reported.

Consistency of sleep onset and offset timing is important for health, safety, and performance, and when insufficient sleep is obtained during the week/work days, weekend/non-work day catch-up sleep may be beneficial.

Mammalian sleep expression and regulation have historically been thought to reflect the activity of neurons. Changes in other brain cells (glia) across the sleep-wake cycle and their role in sleep regulation are comparatively unexplored. We show that sleep and wakefulness are accompanied by state-dependent changes in astroglial activity. Using a miniature microscope in freely behaving mice and a two-photon microscope in head-fixed, unanesthetized mice, we show that astroglial calcium signals are highest in wake and lowest in sleep and are most pronounced in astroglial processes. We also find t...

U-Sleep is a publicly available, ready-to-use deep-learning-based system for automated sleep staging, which was trained and evaluated on PSG recordings from 15,660 participants of 16 clinical studies and can provide highly accurate segmentations when human expertize is lacking.

The findings of this review warrant the need for further research of the outlined dimensions of sleep, and future research would benefit from clarity on definitions across the different dimensions, along with the use of valid and reliable tools.

There is a significant need for greater emphasis on sleep health in education, clinical practice, inpatient and long-term care, public health promotion, and the workplace.

The state-of-the-art in sleep-monitoring technologies are introduced, the opportunities and challenges from data acquisition to the eventual application of insights in clinical and consumer settings are discussed, and the strengths and limitations of current and emerging sensing methods are explored.

Results indicate that DRD1 rs686 may potentially affect predisposition to SB, that H TR2A rs6313 SNP may be involved in SB pathogenesis, and that HTR2Ars2770304 polymorphism might contribute to the association between SB and OSA.

The included studies focused on exploring the effect of physical activity on sleep quality and sleep disorders or the association between physical activity and sleep outcomes, and have potential implications for healthcare, public health policies, and health promotion.

Although a variety of important sleep disorders may disrupt quality of sleep in adolescents, such as obstructive sleep apnea, restless leg syndrome, and narcolepsy, this article will focus on common disorders that affect the quantity of sleep, suchAs poor sleep hygiene, circadian rhythm disorders, and insomnia.

In a prospective study, long sleep duration was associated with increased risk of total and ischemic stroke, whereas short sleep was linked to increase risk of intracerebral hemorrhage, and the Mendelian randomization analysis did not show a significant detrimental effect of short or long sleepduration on the risk oftotal stroke or stroke types.

Advances in the study of sleep in Drosophila are reviewed, their implications for understanding the fundamental functions of sleep that are likely to be conserved among animal species, and important unanswered questions in the field are identified.

By focusing on the components of REM sleep and discouraging continued reliance on a restricted template, this work aims to promote a richer and more biologically grounded developmental-comparative approach that spans behavioral, physiological, neural, and ecological domains.

The prevalence of poor sleep is highlighted, its impacts are described, and the issue of sport culture surrounding healthy sleep is addressed as an important part of training and recovery.

Biological needs for sleep are met by engaging in behaviors that are largely influenced by the environment, social norms and demands, and societal influences and pressures. Insufficient sleep duration and sleep disorders such as insomnia and sleep apnea are highly prevalent in the US population. This article outlines some of these downstream factors, including cardiovascular and metabolic disease risk, neurocognitive dysfunction, and mortality, as well as societal factors such as age, sex, race/ethnicity, and socioeconomics. This review also discusses societal factors related to sleep, such as...

Because many older adults have several factors from different domains affecting their sleep, these complaints are best approached as a multifactorial geriatric health condition, necessitating a multifaceted treatment approach.

Exposure to sleep difficulties varies by age, sex, race/ethnicity, and socioeconomic status; significant sleep health disparities exist in the population.

Advances in research on memory and sleep can shed light on how this processing influences the authors' waking life, which can further inspire the development of novel strategies for decreasing detrimental rumination-like activity during sleep and for promoting beneficial sleep cognition.