Incidence of adverse drug events and potential adverse drug events

Abstract

To assess the association between bicycle helmet legislation and bicycle-related deaths sustained by children involved in bicycle–motor vehicle collisions.We conducted a cross-sectional study of all bicyclists aged 0-16 years included in the Fatality Analysis Reporting System who died between January 1999 and December 2010. We compared fatality rates in age-specific state populations between states with helmet laws and those without helmet laws. We used a clustered Poisson multivariate regression model to adjust for factors previously associated with rates of motor vehicle fatalities: elderly driver licensure laws, legal blood alcohol limit (0.08% between states with helmet laws and those without helmet laws. The mean unadjusted fatality rate was lower in states with helmet laws (2.0/1 000 000 vs 2.5/1 000 000; P = .03). After adjusting for potential confounding factors, lower fatality rates persisted in states with mandatory helmet laws (adjusted incidence rate ratio, 0.84; 95% CI, 0.70-0.98).Bicycle helmet safety laws are associated with a lower incidence of fatalities in child cyclists involved in bicycle–motor vehicle collisions.