The ontogenetic development of the follicular dendritic cell
Cell and Tissue ResearchPublished 1 April 1984
C.D. Dijkstra, E. W. A. Kamperdijk, E.A. D�pp
Citations68
SJR quartileQ1
SJR score1.18
SNIP0.94
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TL;DR
Results strongly suggest that the follicular dendritic cell originates from a reticulum cell, forming the stroma of primary follicles of spleens.
Abstract
After intravenous injection of horseradish peroxidase (HRP)-anti-HRP complexes in 21-day-old rats, complex trapping occurs on reticulum cells, forming the stroma of primary follicles of spleens. After intravenous injection of the same complexes in young adult rats (48 days old), trapping occurs on characteristic follicular dendritic cells (FDCs) located in well-developed germinal centers. These results strongly suggest that the follicular dendritic cell originates from a reticulum cell.
Keywords
Immunology and Microbiology
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