Phase-resetting a mosquito circadian oscillator
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TL;DR
The corkscrew shape of the oscillator's phase-resetting surface, predicted by the Culex model and verified here, suggests that the circadian dynamic system has a limit cycle.
Abstract
TheCulex flight activity circadian oscillator, free-running in darkness, was perturbed by single bright light pulses. The phase and duration of the pulse were varied systematically (Winfree's "singularity trap" procedure) revealing the oscillator's phase-resetting surface. The corkscrew shape of this surface, predicted by theCulex model and verified here, suggests that the circadian dynamic system has a limit cycle.
