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Vulnerability of developing brain

British Journal Of NutritionPublished 1 July 1972Open access
B.P.F. Adlard, John Dobbing
Citations198
SJR quartileQ2
SJR score0.90
SNIP0.91
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TL;DR

It is concluded that undernutrition during the period of most rapid brain growth results in a lasting change in both the concentration and total activity of AChE in the brain.

Abstract

I. Acetylcholinesterase (AChE; EC 3 . I . I . 7) activity was determined in the forebrain, cerebellum and brain stem of 12-week-old rats having different nutritional histories. One group (control) was well fed throughout life. A second group (rehabilitated) was undernourished during the foetal and suckling periods, but fed ad lib. after weaning. A third group (undernourished) was subjected to nutritional growth retardation throughout life.

Keywords

Neuroscience