Ethanol drinking by rhesus monkeys as a function of concentration
PsychopharmacologyPublished 1 January 1978
Jack E. Henningfield, Richard A. Meisch
Citations45
SJR quartileQ1
SJR score1.16
SNIP0.97
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TL;DR
Ethanol deliveries maintained fixed-ratio responding of three rhesus monkeys during daily 3-h sessions, and number of liquid deliveries decreased, although intake of ethanol (g/kg/session) increased somewhat.
Abstract
Ethanol deliveries maintained fixed-ratio (FR) responding of three rhesus monkeys during daily 3-h sessions. At FR values of 8 or 16, ethanol concentration was varied in the sequence 0 (water), 8, 11.3, 16, 22.6 32, 8, and 0% (w/v). As the ethanol concentration increased, number of liquid deliveries decreased somewhat. Blood ethanol levels were usually greater than 200 mg% and occasionally greater than 300 mg%.
Keywords
PsychologyAgricultural and Biological SciencesNeuroscience
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53 Citations1974Richard A. Meisch, Travis Thompson
After one previous session with ethanol, rats' responding for ethanol during the first 2 h of a session substantially exceed water baseline rates, indicating that ethanol had been established as a reinforcer, and results confirm that ethanol was functioning asa reinforcer.
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The data indicate that the progressive decline in codeine-reinforced responding is not the result of a generalized disruption of responding, and both codeine and ethanol showed within-session decreases in responding across the range of reinforcer doses.