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Displaying the in formation contents of structural RNA alignments: the structure logos

Computer applications in the biosciencesPublished 1 January 1997Open access
Jan Gorodkin, Laurie J. Heyer, Søren Brunak, G.D. Storomo
Citations162
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TL;DR

The standard 'Sequence Logo' method is extended to incorporate prior frequencies on the bases, allow for gaps in the alignments, and indicate the mutual information of base-paired regions in RNA.

Abstract

The code is available from, and an Internet server can be used to run the program at, http://www.cbs.dtu.dk/gorodkin/appl/slogo. html.

Keywords

Biochemistry, Genetics and Molecular Biology