During stepwise cue deletion, rat place behaviors correlate with place unit responses
Brain ResearchPublished 1 March 1985
Richard M. Pico, Lauren K. Gerbrandt, Marc Pondel, Gwen O. Ivy
Citations59
SJR quartileQ2
SJR score0.85
SNIP0.72
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TL;DR
The results indicate that the behavioral expressions of place knowledge relate to the responsiveness of hippocampal place cells, which is consistent with the number of absent stimuli.
Abstract
The place behaviors of intact rats, and of those receiving fornix lesions, were examined in the radial-arm maze. A cue-restricted environment was constructed wherein the location of arms with food rewards were identifiable only by their position in relation to an intermittently rotated 4-cue set. Food obtainment was measured during a procedure in which either 1, 2 or 3 of the cues were removed during a block of test sessions. Control animals demonstrated place navigation abilities robust to the deletion of any 1 or 2 cues. The performance of lesioned rats declined in a manner consistent with the number of absent stimuli. The results indicate that the behavioral expressions of place knowledge relate to the responsiveness of hippocampal place cells.
Keywords
NeuroscienceBiochemistry, Genetics and Molecular Biology
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