Nucleotide sequence of the AIDS virus, LAV
CellPublished 1 January 1985
Simon Wain–Hobson, P. Sonigo, Olivier Danos, Stewart T. Cole, Marc Alizon
Citations1,179
SJR quartileQ1
SJR score22.61
SNIP7.62
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Abstract
The complete 9193-nucleotide sequence of the probable causative agent of AIDS, lymphadenopathy-associated virus (LAV), has been determined. The deduced genetic structure is unique: it shows, in addition to the retroviral gag, pol, and env genes, two novel open reading frames we call Q and F. Remarkably, Q is located between pol and env and F is half-encoded by the U3 element of the LTR. These data place LAV apart from the previously characterized family of human T cell leukemia/lymphoma viruses.
Keywords
Immunology and MicrobiologyAgricultural and Biological Sciences
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