login

Clustered Third-Base Substitutions Among Wild Strains of <i>Escherichia coli</i>

SciencePublished 22 July 1983
Roger Milkman, Irving P. Crawford
Citations77
SJR quartileQ1
SJR score10.42
SNIP6.62

TL;DR

Nucleotide sequences of translated regions of the trp operon in 12 wild strains of Escherichia coli reveal striking uniformity among eight strains and clustered substitutions in four strains, suggesting recent common ancestry and supporting the importance of periodic selection in natural populations.

Abstract

Nucleotide sequences of translated regions of the trp operon in 12 wild strains of Escherichia coli reveal striking uniformity among eight strains (suggesting recent common ancestry and supporting the importance of periodic selection in natural populations) and clustered substitutions in four strains (implicating events affecting runs of nucleotides).

Keywords

Biochemistry, Genetics and Molecular Biology