Antimicrobial pterocarpans of nigerian Erythrina mildbraedii
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TL;DR
Bioassay-directed fractionation of ethanolic extracts of the roots of Erythrina mildbraedii resulted in the isolation of the previously known pterocarpans erythrabyssin-II and isoneorautenol and the new pterOCarpan erybraedins A, B, and C, and their in vitro antimicrobial spectra and potencies are reported.
Abstract
Bioassay-directed fractionation of ethanolic extracts of the roots of Erythrina mildbraedii, a plant used in the indigenous system of medicine in Nigeria, resulted in the isolation of the previously known pterocarpans erythrabyssin-II and isoneorautenol and the new pterocarpans erybraedins A, B, and C. The structures of the new compounds were determined by chemical transformations and/or spectroscopy and their in vitro antimicrobial spectra and potencies are reported.