A Clinical Trial Comparing Three Antithrombotic-Drug Regimens after Coronary-Artery Stenting
New England Journal of MedicinePublished 3 December 1998Open access
Martin B. Leon, Donald S. Baim, Jeffrey J. Popma, Paul Gordon, Donald E. Cutlip, Kalon K.L. Ho
Citations1,808
SJR quartileQ1
SJR score19.08
SNIP13.47
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TL;DR
This study compared the efficacy and safety of three antithrombotic-drug regimens — aspirin alone, aspirin and warfarin, and aspirin and ticlopidine — after coronary stenting to prevent stent thrombosis.
Abstract
As compared with aspirin alone and a combination of aspirin and warfarin, treatment with aspirin and ticlopidine resulted in a lower rate of stent thrombosis, although there were more hemorrhagic complications than with aspirin alone. After coronary stenting, aspirin and ticlopidine should be considered for the prevention of the serious complication of stent thrombosis.
Keywords
Medicine
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