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Eszopiclone Co-Administered With Fluoxetine in Patients With Insomnia Coexisting With Major Depressive Disorder

Biological PsychiatryPublished 5 April 2006
Maurizio Fava, W. Vaughn McCall, Andrew D. Krystal, Thomas Wessel, Robert Rubens, Judy Caron
Citations469
SJR quartileQ1
SJR score4.68
SNIP2.24

TL;DR

Eszopiclone/fluoxetine co-therapy was relatively well tolerated and associated with rapid, substantial, and sustained sleep improvement, a faster onset of antidepressant response on the basis of CGI, and a greater magnitude of the antidepressant effect.

Abstract

In this study, eszopiclone/fluoxetine co-therapy was relatively well tolerated and associated with rapid, substantial, and sustained sleep improvement, a faster onset of antidepressant response on the basis of CGI, and a greater magnitude of the antidepressant effect.

Keywords

PsychologySocial SciencesMedicine