Calorimetric and nuclear magnetic resonance study of the phase behaviour of dilauroylphosphatidylcholine/water
Biochimica et Biophysica Acta (BBA) - BiomembranesPublished 1 November 1987
Michael R. Morrow, James H. Davis
Citations28
SJR quartileQ1
SJR score0.81
SNIP0.77
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Abstract
The phase behaviour of 1,2-dilauroyl-sn-glycero-3-phosphocholine (DLPC) has been investigated by high sensitivity differential scanning calorimetry, 2H nuclear magnetic resonance and X-ray diffraction. Depending on the thermal history of the sample, as many as three specific heat maxima are observed by DSC. Only two of these occur after prolonged incubation at temperatures below −6° C or after repeated temperature cycling. The total enthalpy of these two peaks, 6.75 kcal/mol DLPC, and the changes in orientational order observed by 2H-NMR, suggest that both of these peaks involve hydrocarbon chain melting and the structural reorganization that occurs in the sub-transition of longer chain diacylPC.
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