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A kinetic hairpin transfer model for parvoviral DNA replication

Journal of Molecular BiologyPublished 1 July 1989
Katherine C. Chen, John J. Tyson, Muriel Lederman, Ernest R. Stout, Robert C. Bates
Citations27
SJR quartileQ1
SJR score2.21
SNIP1.13

TL;DR

A kinetic model, based on differential rates of hairpin transfer at 3' termini, is described and shown to account for all known parvoviral DNA distributions.

Abstract

The DNAs encapsidated by parvoviruses show distinctly different patterns with respect to the ratio of plus-to-minus strands and sequence heterogeneity at the ends. A kinetic model, based on differential rates of hairpin transfer at 3' termini, is described and shown to account for all known parvoviral DNA distributions.

Keywords

MedicineBiochemistry, Genetics and Molecular Biology