Interferon-alpha–induced changes in tryptophan metabolism
Biological PsychiatryPublished 17 October 2003
Lucile Capuron, Gabriele Neurauter, Dominique L. Musselman, David H. Lawson, Charles B. Nemeroff, Dietmar Fuchs
Citations486
SJR quartileQ1
SJR score4.68
SNIP2.24
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TL;DR
The results suggest that reduced TRP availability plays a role in IFN-alpha-induced depressive symptoms, and paroxetine, although not altering the KYN or neopterin response to IFn-alpha, attenuates the behavioral consequences ofIFN- alpha-mediated TRP depletion.
Abstract
The results suggest that reduced TRP availability plays a role in IFN-alpha-induced depressive symptoms, and paroxetine, although not altering the KYN or neopterin response to IFN-alpha, attenuates the behavioral consequences of IFN-alpha-mediated TRP depletion.
Keywords
MedicineNeuroscience
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