Regulation of Human Affective Responses by Anterior Cingulate and Limbic µ-Opioid Neurotransmission
Archives of General PsychiatryPublished 1 November 2003
Jon‐Kar Zubieta, Terence A. Ketter, Joshua A. Bueller, Yanjun Xu, Michael R. Kilbourn, Elizabeth A. Young
Citations380
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TL;DR
The role of the mu-opioid receptor system in the physiological regulation of affective experiences in humans is confirmed and dynamic changes in mu-OPioid neurotransmission in response to an experimentally induced negative affective state are demonstrated.
Abstract
These data demonstrate dynamic changes in mu-opioid neurotransmission in response to an experimentally induced negative affective state. The direction and localization of these responses confirms the role of the mu-opioid receptor system in the physiological regulation of affective experiences in humans.
Keywords
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