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Effect of homocysteine-lowering treatment with folic acid plus vitamin B6 on progression of subclinical atherosclerosis: a randomised, placebo-controlled trial

The LancetPublished 1 February 2000
E.G. Vermeulen, CDA Stehouwer, J.W.R. Twisk, M. van den Berg, SC de Jong, AJC Mackaay
Citations324
SJR quartileQ1
SJR score12.11
SNIP22.72

TL;DR

Homocysteine-lowering treatment with folic acid plus vitamin B6 in healthy siblings of patients with premature atherothrombotic disease is associated with a decreased occurrence of abnormal exercise electrocardiography tests, which is consistent with a decreases risk of atherosclerotic coronary events.

Abstract

Homocysteine-lowering treatment with folic acid plus vitamin B6 in healthy siblings of patients with premature atherothrombotic disease is associated with a decreased occurrence of abnormal exercise electrocardiography tests, which is consistent with a decreased risk of atherosclerotic coronary events.

Keywords

MedicineBiochemistry, Genetics and Molecular Biology