The site of impulse initiation in a nerve cell of a crustacean stretch receptor
The Journal of PhysiologyPublished 29 August 1958Open access
C. Edwards, David Ottoson
Citations169
Generate an AI Snapshot to get a quick, structured summary of this paper.
Study Snapshot
ObjectiveStudy objective
MethodsResearch methodology
PopulationPopulation studied
Sample sizeSample sizes
OutcomesStudy outcomes here
ResultsStudy results comes here
LimitationsResearch study limitations comes here
A concise AI-generated summary of the paper will appear here once you click Generate AI Snapshot.
TL;DR
Investigation of the site of impulse initiation in the nerve cell of the crustacean stretch receptor concluded that the conducted impulse usually arose in the dendrites or cell body soma, and that only during strong excitation did the impulse arise in the initial portion of the axon.
Keywords
NeuroscienceBiochemistry, Genetics and Molecular Biology
Medical EpigeneticsEpigenetic Regulations of GABAergic Neurotransmission: Relevance for Neurological Disorders and Epigenetic Therapy
8,959 Citations2016Shikshya Shrestha, Steven M. Offer
How various genetic and epigenetic events regulate the GABAergic genes in pre- and postnatal brain contribute to the pathogenesis of neurological disorders and can be used in the development of potential epigenetic therapy for these diseases.
The Journal of General PhysiologyPROCESSES OF EXCITATION IN THE DENDRITES AND IN THE SOMA OF SINGLE ISOLATED SENSORY NERVE CELLS OF THE LOBSTER AND CRAYFISH
446 Citations1955C. Eyzaguirre, Stephen W. Kuffler
The stretch receptor organs of Alexandrowicz in lobster and crayfish possess sensory neurons which have their cell bodies in the periphery and it is concluded that, once threshold excitation is reached, the generator potential within slow cell dendrites is well maintained for the duration of stretch.
The Journal of PhysiologyThe interpretation of spike potentials of motoneurones
377 Citations1957J. S. Coombs, Daniel Curtis +1 more
The Journal of General PhysiologySTEPS IN THE PRODUCTION OF MOTONEURON SPIKES
315 Citations1957M. G. F. Fuortes, K. Frank +1 more
Curves of the strength of the stimuli required for eliciting small or full spikes have been constructed in a number of conditions and it is assumed that threshold of the major portions of the soma membrane is higher than the threshold ofThe axon, the transition occurring over a finite area near the axon hillock.
The Journal of PhysiologyThe generation of impulses in motoneurones
308 Citations1957J. S. Coombs, D.R. Curtis +1 more
An attempt to determine the factors governing the generation of spike potentials in these three components, and the way in which they are related to the discharge of an impulse down the axon of the motoneurone.
The Journal of General PhysiologySYNAPTIC INHIBITION IN AN ISOLATED NERVE CELL
288 Citations1955Stephen W. Kuffler, C. Eyzaguirre
The results support previous conclusions that during stretch the dendrites provide a persisting "drive" for the more central portions of the receptor cell, and that antidromic all-or-none impulses do not penetrate into the distal portions of stretch-depolarized dendrite.
The Journal of General PhysiologyFURTHER STUDY OF SOMA, DENDRITE, AND AXON EXCITATION IN SINGLE NEURONS
179 Citations1955C. Eyzaguirre, Stephen W. Kuffler
The present investigation continues a previous study in which the soma-dendrite system of sensory neurons was excited by stretch deformation of the peripheral dendrite portions, and it is thought that normally the over-all duration of axon impulses is shorter.
Reviews of physiology, biochemistry and pharmacologyA neurophysiological interpretation of the respiratory act
119 Citations1940Robert Gesell
The Journal of General PhysiologyA PERFUSING SOLUTION FOR THE LOBSTER (HOMARUS) HEART AND THE EFFECTS OF ITS CONSTITUENT IONS ON THE HEART
106 Citations1941William H. Cole
All inorganic perfusing solution for the heart of the lobster Homarus americanus, to allow prolonged normal beating (20 hours or more) must agree closely with the inorganic composition of the serum, which varies differentially with that of the environmental sea water.
Proceedings of the Royal Society of London. Series B, Biological sciencesSynaptic transmission. An analysis of the electrical activity of the lateral geniculate nucleus in the cat after optic nerve stimulation
85 Citations1953P. O. Bishop
It is concluded that the presence of a positive synaptic potential indicates that the proximal portions of the axons are acting as sources of current for sinks in the region of the dendrites and cell bodies in the cat's optic nerve.