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Definition, course, and outcome of mild cognitive impairment

Aging Neuropsychology and CognitionPublished 1 April 1996
Glenn E. Smith, Ronald C. Petersen, Joseph E. Parisi, Robert J. Ivnik, Emre Kokmen, Eric G. Tangalos
Citations187
SJR quartileQ2
SJR score0.64
SNIP0.80

TL;DR

Biologic and cognitive parameters including Apolipoprotein E genotype help to differentiate MCI persons who will progress to dementia in 2-4 years from those who will remain free from dementia over this interval.

Abstract

Abstract Mild Cognitive Impairment (MCI) is a term which can be applied to a boundary area between dementia and normal aging. Criteria which reliably describe persons falling in this range of the cognitive continuum can be defined. These persons are at very high risk for developing dementia. Biologic and cognitive parameters including Apolipoprotein E genotype help to differentiate MCI persons who will progress to dementia in 2-4 years from those who will remain free from dementia over this interval.

Keywords

MedicineNeuroscience