Epidemiological evidence for causal relationship between Epstein-Barr virus and Burkitt's lymphoma from Ugandan prospective study
NaturePublished 1 August 1978
G de-Thé, A. Geser, Nicholas Day, P. M. Tukei, Edward H. Williams, D. Beri
Citations612
SJR quartileQ1
SJR score18.29
SNIP10.16
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TL;DR
Results from a prospective sero-epidemiological study initiated in Uganda in 1971 indicate that children with high antibody titres to Epstein-Barr virus structural antigens are at high risk of developing Burkitt's lymphoma.
Abstract
Results from a prospective sero-epidemiological study initiated in Uganda in 1971 indicate that children with high antibody titres to Epstein-Barr virus structural antigens are at high risk of developing Burkitt's lymphoma. These findings strongly support a causal relationship between the Epstein-Barr virus and Burkitt's lymphoma but suggest that the oncogenic potential of the virus is realised only in exceptional circumstances.
Keywords
Medicine
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