Copulatory behavior in male rats following amygdaloid lesions

Abstract

Surviving in the animal kingdom hinges on the ability to fight competitors and to mate with partners. Dedicated neural circuits in the brain allow animals to mate and attack without any prior experience. Classical lesioning and stimulation studies demonstrated that medial hypothalamic and limbic areas are crucial for male sexual and aggressive behaviors. Moreover, recent functional manipulation tools have uncovered neural circuits critical for mating and aggression, and optical and electrophysiological recordings have revealed how socially relevant information (e.g. sex-specific sensory signals, action commands for specific behaviors, mating- and aggression-specific motivational states) is encoded in these circuits. A better understanding of the neural mechanisms of innate social behaviors will provide critical insights to how complex behavioral outputs are coordinated at the circuit level. In this paper, I review these recent studies and discuss the potential circuit logic of male sexual and aggressive behaviors in mice.