Waking Quantitative Electroencephalogram and Auditory Event-Related Potentials Following Experimentally Induced Sleep Fragmentation
SLEEPPublished 1 September 2003
Kimberly A. Côté, Catherine E. Milner, Stephanie L. Osip, L. Bryan Ray, Karen D. Baxter
Citations50
SJR quartileQ1
SJR score1.80
SNIP1.63
Generate an AI Snapshot to get a quick, structured summary of this paper.
Study Snapshot
ObjectiveStudy objective
MethodsResearch methodology
PopulationPopulation studied
Sample sizeSample sizes
OutcomesStudy outcomes here
ResultsStudy results comes here
LimitationsResearch study limitations comes here
A concise AI-generated summary of the paper will appear here once you click Generate AI Snapshot.
TL;DR
Electroencephalographic and event-related potentials data illustrate impairment in information-processing capabilities associated with reduced arousal elicited by experimental sleep fragmentation, which leads to sustained impairment in alertness and attention.
Abstract
Electroencephalographic and event-related potentials data illustrate impairment in information-processing capabilities associated with reduced arousal elicited by experimental sleep fragmentation. This subtle degree of sleep disruption, where total sleep time is not reduced, leads to sustained impairment in alertness and attention.
Keywords
PsychologyNeuroscience
Archives of General PsychiatryAn Inventory for Measuring Depression
38,163 Citations1961Aaron T. Beck
The difficulties inherent in obtaining consistent and adequate diagnoses for the purposes of research and therapy have been pointed out and a wide variety of psychiatric rating scales have been developed.
Journal of Personality and Social PsychologyDevelopment and validation of brief measures of positive and negative affect: The PANAS scales.
31,665 Citations1988David Watson, Lee A. Clark +1 more
PsychophysiologyQuantification of Sleepiness: A New Approach
2,555 Citations1973Eric Hoddes, Vincent P. Zarcone +3 more
SLEEPCumulative Sleepiness, Mood Disturbance, and Psychomotor Vigilance Performance Decrements During a Week of Sleep Restricted to 4–5 Hours per Night
2,037 Citations1997David F. Dinges, Frances M. Pack +6 more
It is suggested that cumulative nocturnal sleep debt had a dynamic and escalating analog in cumulative daytime sleepiness and that asymptotic or steady-state sleepiness was not achieved in response to sleep restriction.
SLEEPEffect of Sleep Disruption on Sleep, Performance, and Mood
367 Citations1985Michael H. Bonnet
It was concluded that periodic disruption of sleep, perhaps by destroying sleep continuity, quickly results in impaired function and may help explain function loss in severe sleep apneics.
SLEEPPower Density in Theta/Alpha Frequencies of the Waking EEG Progressively Increases During Sustained Wakefulness
348 Citations1995Christian Cajochen, Daniel P. Brunner +3 more
Fatigue ratings and the theta/ alpha power density of the waking EEG recorded at the same four time points during the constant routine protocol correlated significantly, demonstrating the presence of a homeostatic component in the control of EEG power density in the 6.25- to 9.0-Hz range.
American Journal of Physiology-Regulatory, Integrative and Comparative PhysiologyEEG and ocular correlates of circadian melatonin phase and human performance decrements during sleep loss
347 Citations1999Christian Cajochen, Sat Bir S. Khalsa +3 more
The data indicate that frontal areas of the brain are more susceptible to sleep loss than occipital areas and frontal EEG activity and ocular parameters may be used to monitor and predict changes in neurobehavioral performance associated with sleep loss and circadian misalignment.
SLEEPSleep Fragmentation and Daytime Sleepiness
346 Citations1984Edward Stepanski, James Lamphere +3 more
The number and type of nocturnal arousals play an important role in subsequent daytime sleepiness and, depending upon the sleep complaint, different types of arousals are predictive of degree of daytimeSleepiness.
American Journal of Respiratory and Critical Care MedicineThe Effect of Sleep Fragmentation on Daytime Function
328 Citations1996Sascha E. Martin, H M Engleman +2 more
One night of sleep fragmentation makes normal subjects sleepier during the day, impairs their subjective assessment of mood, and decreases mental flexibility and sustained attention.
SLEEPThe Effect of Sleep Fragmentation on Daytime Function
260 Citations2002Edward Stepanski
It is clear from this literature that fragmented sleep is less restorative than consolidated sleep, and leads to sleepiness-related daytime impairment, and more studies are needed that evaluate "sub-cortical" arousals, EEG arousals and daytime function simultaneously.
PsychophysiologyPerformance and Sleepiness as a Function of Frequency and Placement of Sleep Disruption
231 Citations1986Michael H. Bonnet
It was concluded that the data were most parsimoniously explained by the Sleep Continuity Theory—i.e., that periods of uninterrupted sleep in excess of 10 min are required for sleep to be restorative.
Journal of Applied PhysiologyMetabolism during normal, fragmented, and recovery sleep
150 Citations1991Michael H. Bonnet, Richard B. Berry +1 more
Average metabolic data were obtained for each 3-min period during consecutive nights of normal, experimentally fragmented, and recovery sleep in a group of 12 normal young adult males to infer that increased metabolism during sleep causes nonrestorative sleep.
SLEEPEffect of Total Sleep Deprivation on Reaction Time and Waking EEG Activity in Man
150 Citations1995Ivan Lorenzo, Jorge Luis López Ramos +3 more
The present findings show a linear increase in EEG power and RT with TSD, and a diurnal oscillation of EEG power, which is independent of TSD.
SLEEPExperimental Sleep Fragmentation
137 Citations1994T Roehrs, Lori Merlotti +3 more
In the last 3 hours of sleep versus the first 3 hours, arousals occurred less frequently, required more tones to produce, resulted in shorter durations and in fewer sleep stage changes, except for REM sleep where the converse was the case.
Neurobiology of AgingThe effect of sleep fragmentation on sleep and performance in younger and older subjects
128 Citations1989Michael H. Bonnet
It was concluded that, while both age groups were sensitive to moderate sleep disturbance, the older individuals appeared somewhat less sensitive than the young adults.
International Journal of NeuroscienceExperimental sleep fragmentation in normal subjects
127 Citations1987Edward J. Stepanski, James Lamphere +3 more
The MSLT showed statistically significant changes after two nights of fragmented sleep, but the three fragmentation schedules did not differ from each other.
SLEEPSleep Fragmentation in Normals: A Model for Sleepiness Associated With Upper Airway Resistance Syndrome
117 Citations1994Pierre Philip, Riccardo Stoohs +1 more
Eight young adults underwent 1 night of auditory sleep fragmentation followed by four naps of the multiple sleep latency test and performance testing the next day to mimic as closely as possible the nocturnal sleep disruption seen in subjects with upper airway resistance syndrome.
SLEEPSleep Restoration as a Function of Periodic Awakening, Movement, or Electroencephalographic Change
114 Citations1987Michael H. Bonnet
The data were interpreted as providing evidence that the restorative function of sleep is equally impaired by any periodic change in ongoing EEG and that impairment does not require a return to waking consciousness.
PubMedFragmenting sleep diminishes its recuperative value.
114 Citations1987Brian J. Levine, T Roehrs +3 more
Journal of Sleep ResearchDoes sleep fragmentation impact recuperation?A review and reanalysis
110 Citations1999Nancy J. Wesensten, Thomas J. Balkin +1 more
It is shown that when stage 1 sleep is excluded from TST, a stronger relationship between TST and subsequent alertness and performance emerges – and the need to invoke ‘sleep continuity’ as a variable that contributes independently to recuperative sleep processes is obviated.
SLEEPPerformance During Frequent Sleep Disruption
108 Citations1987Ralph Downey, Michael H. Bonnet
Sleep stages (slow-wave sleep, SWS + REM (SWSR), and total sleep time minus stage 1 sleep) were poor predictors of performance changes across the 2 disruption nights, and arousal threshold was significantly positively correlated with response latency.
Physiology & BehaviorPerformance and sleepiness following moderate sleep disruption and slow wave sleep deprivation
106 Citations1986Michael H. Bonnet
To determine whether the amount of SWS rather than the periodic disruption of sleep accounts for decreased performance of Ss with disrupted sleep, normal young adults spent two 4-night periods in the laboratory.
Work & StressA new quantitative method for assessing sleepiness: The alpha attenuation test
99 Citations1995Claudio Stampi, Polly Stone +1 more
In this validation study, the AAT proved to be a sensitive measure of sleepiness induced by sleep deprivation, and it also correlated well with the Multiple Sleep Latency Test.
PubMedThe P300 event-related potential. The effects of sleep deprivation.
98 Citations1992Alana Morris, Yuen T. So +3 more
The P3 potential is a more cognitive measure of sleep deprivation than reaction time, a measure commonly used in previous studies, and is recommended as a marker to examine sleep deprivation in health professionals.
SLEEPTime Course of Reaction Time and EEG While Performing a Vigilance Task During Total Sleep Deprivation
93 Citations1996María Corsi‐Cabrera, C. Arce +3 more
The results demonstrate that the increment in RT is associated with the increase in AP, particularly in the left central cortex; that the EEG may be used to identify sleepiness; and that EEG during task performance is more sensitive to TSD than during relaxed wakefulness.
Physiology & BehaviorInfrequent periodic sleep disruption: Effects on sleep, performance and mood
87 Citations1989Michael H. Bonnet
The data from both experiments were interpreted as support for sleep continuity theory; i.e., as the length of periods of consolidated sleep decrease, residual decrements increase.
SLEEPChanges in the Waking EEG as a Consequence of Sleep and Sleep Deprivation
71 Citations1992María Corsi‐Cabrera, Jorge Luis López Ramos +4 more
EEG activity during wakefulness is a sensitive parameter and a useful tool to assess the consequences of sleep on brain functional organization and after diurnal and nocturnal sleep as compared to sleep deprivation, where interhemispheric correlations were higher and intrahemispherical correlations were lower.
Journal of Sleep ResearchThe effect of sleep fragmentation on cognitive processing using computerized topographic brain mapping
56 Citations2000Ruth N. Kingshott, Richard Cosway +2 more
Reductions in P300 amplitudes with sleep fragmentation in frontal, central and temporal brain areas suggest that sleep fragmentation may cause a broad decrease in attention.
Biological PsychologyThe effects of sleep loss on task performance and the electroencephalogram in young and elderly subjects
55 Citations1997Fren T.Y. Smulders, J. Leon Kenemans +2 more
The results suggest that the detrimental effects of sleep loss are smaller in the elderly, which is consistent with an inverted-U relationship between arousal and performance.
Human Factors The Journal of the Human Factors and Ergonomics SocietyInfluence of Extended Wakefulness on Automatic and Nonautomatic Processing
48 Citations1994Darryl G. Humphrey, Arthur F. Kramer +1 more
Overall performance declined with extended wakefulness, but the benefits of consistently mapped training were retained throughout the night, and reaction time and event-related brain potentials measures suggest that the locus of extended wakeful effects was during early perceptual processes.
PsychophysiologyChanges in the scalp topography of event‐related potentials and behavioral responses during the sleep onset period
47 Citations2002Kimberly A. Côté, Duncan R. de Lugt +1 more
P300 is associated with behavioral detection of the target stimulus, whether in wakefulness or stage 1 "sleep," and trials were sorted by reaction time (RT), in which bins 1-3 represented increasingly long RT.
Journal of Sleep ResearchThe effect of clustered versus regular sleep fragmentation on daytime function
36 Citations1999Sascha E. Martin, Pirkko Brander +2 more
The results suggest that although there is more slow wave sleep (SWS) on the clustered night, similar numbers of sleep fragmenting events produced similar daytime function whether the events were evenly spaced or clustered.
Alcoholism Clinical and Experimental ResearchSimple Reaction Time Event‐Related Potentials: Effects of Alcohol and Sleep Deprivation
33 Citations1993Kevin R. Krull, Landgrave T. Smith +2 more
The results suggested that sleep deprivation slowed initial stimulus detection, whereas alcohol slowed later processing and response activation.
SLEEPLong-Latency Auditory Evoked Responses During Sleep Deprivation and in Narcolepsy
27 Citations1982Mark R. Pressman, Arthur J. Spielman +2 more
Electroencephalography and Clinical NeurophysiologyEffect of normal sleep and sleep deprivation on interhemispheric correlation during subsequent wakefulness in man
26 Citations1989María Corsi‐Cabrera, Jorge Luis López Ramos +1 more
EEG activity was recorded from the right and left central, temporal, parietal and occipital derivations in 10 volunteers under the following conditions: at nightbefore going to sleep, at night before sleep deprivation, in the morning after waking, inThe morning after sleep deprivation and in themorning 48 h after recovery.
Work & StressAuditory evoked potentials as a function of sleep deprivation
22 Citations1989John Harsh, Pietro Badia
PsychophysiologyInfluence of Total Sleep Deprivation on Event‐Related Potentials in Man
16 Citations1983Pierre Gauthier, Claude Gottesmann
The unobtainable PINV after sleep deprivation and the low CNV amplitude could suggest a common neurophysiological origin for these two slow potentials.
PsychophysiologyChanges in the scalp topography of event-related potentials and behavioral responses during the sleep onset period
14 Citations2002Kimberly A. Côté, Duncan R. de Lugt +1 more
Journal of the Neurological SciencesPerformance and sleepiness following moderate sleep disruption and slow wave sleep deprivation
12 Citations1986Mike Bonnet