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Therapeutic plasma exchange and intravenous immunoglobulin for obsessive-compulsive disorder and tic disorders in childhood

The LancetPublished 1 October 1999
Susan Perlmutter, Susan F. Leitman, Marjorie A. Garvey, Susan Hamburger, Elad Feldman, Henrietta L. Leonard
Citations560
SJR quartileQ1
SJR score12.11
SNIP22.72

TL;DR

Plasma exchange and IVIG were both effective in lessening of symptom severity for children with infection-triggered OCD and tic disorders.

Abstract

Plasma exchange and IVIG were both effective in lessening of symptom severity for children with infection-triggered OCD and tic disorders. Further studies are needed to determine the active mechanism of these interventions, and to determine which children with OCD and tic disorders will benefit from immunomodulatory therapies.

Keywords

PsychologyMedicine