Amino acid sequence of rat epidermal thiol proteinase inhibitor
Biochemical and Biophysical Research CommunicationsPublished 1 May 1984
Koji Takio, Eiki Kominami, Yoshiaki Bando, Nobuhiko Katunuma, Koiti Titani
Citations67
SJR quartileQ2
SJR score0.75
SNIP0.56
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TL;DR
The protein has a high degree of sequence homology to either rat liver or human leucocyte inhibitor but is not identical and may represent a new type of low molecular weight thiol proteinase inhibitors.
Abstract
The complete amino acid sequence of rat epidermal thiol proteinase inhibitor was determined. The unique 103-residue sequence was derived by analysis of two peptides generated by limited proteolysis of the native inhibitor with Staphylococcus aureus V8 protease and of three cyanogen bromide fragments. The protein has a high degree of sequence homology to either rat liver or human leucocyte inhibitor but is not identical and may represent a new type of low molecular weight thiol proteinase inhibitors.
Keywords
Biochemistry, Genetics and Molecular Biology
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