login

Insulin initiation of lens fiber differentiation in culture: Elongation of embryonic lens epithelial cells

Developmental BiologyPublished 1 January 1973
Joram Piatigorsky
Citations80
SJR quartileQ2
SJR score1.16
SNIP0.73

TL;DR

Insulin replaces serum as a stimulant of cell elongation in the cultured 6-day-old embryonic chick lens epithelium, and this finding should facilitate further analyses of the mechanism of Cell elongation.

Abstract

Insulin replaces serum as a stimulant of cell elongation in the cultured 6-day-old embryonic chick lens epithelium. Thus, cell elongation, which is characteristic of lens fiber differentiation, can now be studied under chemically defined conditions. This finding should facilitate further analyses of the mechanism of cell elongation.

Keywords

MedicineBiochemistry, Genetics and Molecular Biology