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Re-emergence of Chlamydia trachomatis infection after mass antibiotic treatment of a trachoma-endemic Gambian community: a longitudinal study

The LancetPublished 1 April 2005
Matthew J. Burton, Martin J. Holland, Pateh Makalo, Esther Aryee, Neâl Alexander, Ansumana Sillah
Citations140
SJR quartileQ1
SJR score12.11
SNIP22.72

TL;DR

The effect of mass treatment on the conjunctival burden of Chlamydia trachomatis in a Gambian community with low to medium trachoma prevalence and the rate, route, and determinants of re-emergent infection are measured.

Abstract

Mass antibiotic treatment generally results in effective, longlasting control of C trachomatis in this environment. For low prevalence regions, one treatment episode might be sufficient. Infection can be reintroduced through contact with untreated populations. Communities need to be monitored for treatment failure and control measures implemented over wide geographical areas.

Keywords

Immunology and MicrobiologyMedicineBiochemistry, Genetics and Molecular Biology