Effects of low-dose heparin on failure of intravenous infusions in children
Heart & LungPublished 1 January 1995
Alex Wright, John Hecker, Gail T. McDonald
Citations17
SJR quartileQ2
SJR score0.81
SNIP0.87
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TL;DR
Use of solutions containing low-dose heparin is recommended for children who might have problems with venous access, and a dextrose-saline solution manufactured under commercial conditions and containing 1 IU per ml of Heparin prolongs the use of infusion sites in children is recommended.
Abstract
Use of solutions containing low-dose heparin is recommended for children who might have problems with venous access.
Keywords
MedicineHealth Professions
British Journal of CancerDesign and analysis of randomized clinical trials requiring prolonged observation of each patient. II. Analysis and examples
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Efficient methods of analysis of randomized clinical trials in which the authors wish to compare the duration of survival among different groups of patients are described.
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A signficant decrease in the incidence of cannula‐related phlebitis was also noted in patients receiving subcutaneous low dose heparin (5000 units 8‐hourly), which may be due to inhibition of fibrin clot formation around the tip of the indwelling intravenous cannula.
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56 Citations1993
Risks of nonpatency are greatest in women with short nonfemoral lines who do not receive other anticoagulants or thrombolytics and have nonheparinized flush solutions and chances for patency are great in men with long femoral lines, who receive other anti-atherosclerotic drugs and heparinization flush solutions.
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Self-adhesive patches which release glyceryl trinitrate at a slow continuous rate or placebo patches were applied to the skin of patients distal to intravenous infusion sites in a double-blind manner and frequency of infusion failure was three times lower than with placebo patches.
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Final filters can be used to reduce the incidence of phlebitis-related i.v. complications and thereby reduce the length of hospital stay in postoperative patients whose infusions were filtered through inline final filters.
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It will be shown that the complications of local complications of intravenous infusions can be significantly reduced by buffering the infusion fluids.
CHEST JournalPrevention Of Lidocaine-Infusion Phlebitis By Heparin And Hydrocortisone
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It is concluded that infusion of lidocaine causes a high incidence of phlebitis which can be markedly reduced by adding heparin or hydrocortisone (or both) to the infusate and limiting the duration of the infusion in a given vein to 24 hours.
Journal of Paediatrics and Child HealthFailure of intravenous infusions in neonates
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Multivariate analysis suggested that survival was improved with ampicillin and aminophylline and worse for leg sites, for older babies and for infusions in which the fluids were given at greater rater and also indicated that neutralization of TPN improved survival.
Pharmacy World & ScienceOn the efficacy of low dose prednisolone and heparin sodium in the prevention of infusion thrombophlebitis. A double-blind trial
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A prospective, double-blind investigation into the effectiveness of the addition to infusion fluids of an injectable containing 0.3 mg prednisolone and 10 units heparin per ml in a phosphate buffer pH=7·5 versus the phosphate buffer alone is described.
International Journal of Pharmacy PracticeProlonging the survival of peripheral infusion sites in neonates with low dose heparin
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Adding heparin to 10 per cent dextrose and to total parenteral nutrition solutions infused into peripheral veins of premature babies suggests that 0.5iu/ml may be sufficient to prolong the survival of peripheral intravenous sites in premature babies.
