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Hypothalamic-Pituitary-Adrenal Axis Dysregulation in Sexually Abused Girls

Obstetrical & Gynecological SurveyPublished 1 July 1994
Michael D. De Bellis, George P. Chrousos, Lorah D. Dorn, Lillian Burke, Karin F. Helmers, Mitchel A. Kling
Citations160
SJR quartileQ2
SJR score0.57
SNIP1.41

TL;DR

The attenuated plasma ACTH with corresponding robust plasma cortisol responses to oCRH stimulation and normal 24-h UFC measures in sexually abused girls suggest a dysregulatory disorder of the HPA axis in these individuals, which may reflect pituitary hyporesponsiveness to CRH.

Abstract

de Bellis, Michael D.; Chrousos, George P.; Dorn, Lorah D.; Burke, Lillian; Helmers, Karin; Kling, Mitchel A.; Trickett, Penelope K.; Putman, Frank W. Author Information

Keywords

Neuroscience