Factors determining case fatality in myocardial infarction "who dies in a heart attack"?
HeartPublished 1 September 1995Open access
S. Goya Wannamethee, Peter H. Whincup, A. G. Shaper, Mary Walker, P. W. Macfarlane
Citations87
SJR quartileQ1
SJR score1.78
SNIP1.47
Generate an AI Snapshot to get a quick, structured summary of this paper.
Study Snapshot
ObjectiveStudy objective
MethodsResearch methodology
PopulationPopulation studied
Sample sizeSample sizes
OutcomesStudy outcomes here
ResultsStudy results comes here
LimitationsResearch study limitations comes here
A concise AI-generated summary of the paper will appear here once you click Generate AI Snapshot.
TL;DR
It is suggested that physical activity may be an important modifiable factor influencing the incidence of ischaemic heart disease and the chance of survival in men without a previous heart attack or stroke.
Abstract
These findings suggest that physical activity may be an important modifiable factor influencing the incidence of ischaemic heart disease and the chance of survival in men without a previous heart attack or stroke. Arrhythmia, increased heart rate, diabetes, and treatment for hypertension are also areas of concern.
Keywords
Medicine
American Heart JournalHeart rate and cardiovascular mortality: The Framingham study
1,286 Citations1987William B. Kannel, Craig Kannel +2 more
A more impressive association to cardiovascular disease was observed in men than in women, which was independent of associated cardiovascular risk factors, and all-cause, cardiovascular, and coronary mortality rates increased progressively in relation to antecedent heart rates determined biennially.
The LancetALCOHOL AND MORTALITY IN BRITISH MEN: EXPLAINING THE U-SHAPED CURVE
774 Citations1988A. G. Shaper, S. Goya Wannamethee +1 more
There was a U-shaped relationship between alcohol intake and total mortality and an inverse relationship with cardiovascular mortality, even after adjustment for age, cigarette smoking, and social class.
BMJBritish Regional Heart Study: cardiovascular risk factors in middle-aged men in 24 towns.
531 Citations1981A. G. Shaper, Stuart Pocock +4 more
Alcohol intake and body mass index explained only a part of the striking differences between towns in mean blood pressure readings, and some important "town"factors remained unexplained.
JAMAThe Impact of Diabetes on Survival Following Myocardial Infarction in Men vs Women
481 Citations1988Robert D. Abbott
It is concluded that in the diabetic patient who survives an MI, cardiac failure is a common occurrence, warranting early detection and vigorous management in periods of convalescence and follow-up, particularly in women, where its effect on survivorship is considerable.
HeartPhysical activity and ischaemic heart disease in middle-aged British men.
301 Citations1991A. G. Shaper, S. Goya Wannamethee +1 more
Overall, the overall level of physical activity is an important independent protective factor in ischaemic heart disease and that vigorous (sporting) exercise, although beneficial in its own right, is not essential in order to obtain such an effect.
American Journal of Clinical NutritionAlcohol and platelet aggregation: the Caerphilly Prospective Heart Disease Study
286 Citations1992SC Renaud, Andrew D Beswick +3 more
It is suggested that part of the effects of alcohol on coronary heart disease may be mediated by a dose-dependent effect on certain platelet functions, modulated by the intake of dietary fat.
BMJEffect of moderate dose of alcohol with evening meal on fibrinolytic factors
244 Citations1994H. Hendriks, Jan A. Veenstra +3 more
The effects observed in the early morning are consistent with a decrease in risk of coronary heart disease in moderate drinkers.
Cardiology ClinicsIMPACT OF DIFFERENT SPORTS AND TRAINING ON CARDIAC STRUCTURE AND FUNCTION
232 Citations1997Robert Fagard
The consistency of the results of studies on athletes in the competitive and the resting season, of training of sedentary subjects, and of spinal cord-injured patients suggests that variations in physical activity can alter left ventricular structure.
HeartHeart rate, ischaemic heart disease, and sudden cardiac death in middle-aged British men.
195 Citations1993A. G. Shaper, S. Goya Wannamethee +2 more
Raised heart rate is a risk factor for fatal ischaemic heart disease events but particularly for sudden cardiac death, and is most clearly seen in men free of pre-existing ischaemia heart disease at initial examination.
American Heart JournalImpact of atrial fibrillation on the in-hospital and long-term survival of patients with acute myocardial infarction: A community-wide perspective
174 Citations1990Robert J. Goldberg, Dana G. Seeley +7 more
While the crude long-term survival rate for patients with AF was poorer than that of patients without AF for the combined as well as for individual study periods, similar to the in-hospital findings the independent effect of AF on long- term prognosis was not upheld after use of a multivariate analysis.
The American Journal of CardiologyRisk factors for myocardial infarction and death due to ischemic heart disease and other causes
174 Citations1975Gösta Tibblin, Lars Wilhelmsen +1 more
Obesity, the level of physical activity, fasting blood glucose levels, doffee consumption, hematocrit and erythrocyte sedimentation rate had no predictive value for assissing the risk of nonfatal myocardial infarction, fatal ischemic heart disease or death from other causes before age 60.
American Heart JournalThe impact of age on the incidence and prognosis of initial acute myocardial infarction: The Worcester Heart Attack Study
173 Citations1989Robert J. Goldberg, Joel M. Gore +6 more
The results of this population-based study reinforce the need for, and importance of, modification of coronary risk factors in both young and older individuals, and of focused therapeutic efforts to salvage jeopardized myocardium in elderly patients hospitalized with acute MI.
International Journal of EpidemiologyUsing the WHO (Rose) Angina Questionnaire in Cardiovascular Epidemiology
171 Citations1989Derek G. Cook, A. G. Shaper +1 more
In cardiovascular studies of middle-aged men which use the WHO (Rose) questionnaire for the purposes of determining prevalence or assessing risk of a heart attack, angina should include both 'possible' and 'definite' angina.
Diabetes CareTrends in Prevalence of Diabetes Mellitus in Patients with Myocardial Infarction and Effect of Diabetes on Survival: The Minnesota Heart Survey
171 Citations1991J. Michael Sprafka, Gregory L. Burke +3 more
The findings suggest that the risk of coronary heart disease morbidity and mortality attributable to diabetes may be increasing over time and clinicians need to take extra care in the management of MIs in diabetic individuals.
HeartBlood lipids in middle-aged British men.
125 Citations1983Dag S. Thelle, A. G. Shaper +4 more
In this population, body mass index is closely associated with the concentration of blood lipids but its effects are probably indirect and mediated by a complex of dietary and other factors.
Journal of Applied PhysiologyEffects of exercise and conditioning on clotting and fibrinolytic activity in men
110 Citations1987Earl W. Ferguson, L. L. Bernier +3 more
Changes in clotting and fibrinolytic activity before and after maximum exercise on a treadmill according to the Bruce protocol were evaluated and were not significantly correlated with changes in whole blood lactate, blood pyruvate, or rectal temperatures.
Journal of Clinical EpidemiologyThe influence of sex and diabetes mellitus on survival following acute myocardial infarction: A community-wide perspective
90 Citations1993Richard P. Donahue, Robert J. Goldberg +3 more
The "female advantage" observed in the non-diabetic population was eliminated among the diabetic patients and Randomized clinical trials are needed in the diabetic population to identify specific therapies to reduce their increased risk of death.
Diabetes CareDeterminants of Hospital Admission and Case Fatality in Diabetic Patients With Myocardial Infarction
76 Citations1988John Yudkin, George A Oswald
Neither incidence nor case fatality of myocardial infarction in diabetic patients is positively associated with cumulative glycemic exposure and prior blood glucose control, as judged by levels of HbA1c, was not related to hospital outcome.
PubMedFollow-up of subjects in prospective studies based in general practice.
74 Citations1984Mary Walker, A. G. Shaper
The methods used and the difficulties encountered in maintaining the flow of information on these subjects are explained and the problems of removal and tracing are discussed.
Acta Medica ScandinavicaMortality and Morbidity during 13.5 Years' Follow‐up in Relation to Blood Pressure
61 Citations1979Kurt Svärdsudd, Gösta Tibblin
Mortality and morbidity during this time in relation to BP at the time of the initial examination are presented, and there is no indication of a decreasing importance of BP as a risk factor in this age period.
The LancetImpact of hospital thrombolysis policy on out-of-hospital response to suspected myocardial infarction
50 Citations1993Denis Pereira Gray, Jared E. Murdock +3 more
The policy to give thrombolysis to all patients who arrived within 6 hours of the onset of symptoms, in the absence of a specific contraindication, has saved about 8 lives per year, and it is not surprising that there has been no improvement in overall case fatality after myocardial infarction.
Journal of Epidemiology & Community HealthThe philosophical foundations of public health: an invitation to debate.
46 Citations1994Harry G. J. Nijhuis, L J van der Maesen
The similarities in theme between these articles and a recent Editorial in the Journal of Public Health Medicine indicate that critical thinking about epidemiological concepts, methods and meanings is still required.
Cardiology ClinicsImpact of Different Sports and Training on Cardiac Structure and Function
43 Citations1992Robert Fagard
The consistency of the results of studies on athletes in the competitive and the resting season, of training of sedentary subjects, and of spinal cord injured patients suggests that variations in physical activity can alter left ventricular structure.
Journal of Epidemiology & Community HealthIschaemic heart disease: association with haematocrit in the British Regional Heart Study.
42 Citations1994S. Goya Wannamethee, A. G. Shaper +1 more
Risk of major ischaemic heart disease events was significantly increased at haematocrit levels of > or = 46.0%, even after adjustment for age, social class, smoking, body mass index, physical activity, blood cholesterol, lung function, and pre-existing evidence of ischaemia heart disease.
European Heart JournalParental death from heart disease and the risk of heart attack
37 Citations1988A N Phillips, A. G. Shaper +2 more
Men who said their father had died from 'heart trouble' were at twice the risk of a major ischaemic heart disease event compared with men whose fathers were still alive and 1.5 times the chance of men who reported their father to be dead from another or unknown cause.
American Journal of EpidemiologyTRENDS IN CORONARY HEART DISEASE EVENT RATES IN NEW ZEALAND
37 Citations1984Robert Beaglehole, Ruth Bonita +4 more
A significant decline in the rate of sudden death occurred in the Auckland region over the seven-year period from 1974, and was particularly marked in people under the age of 50 years and in subjects with a prior history of myocardial infarction.
American Journal of EpidemiologyISCHEMIC HEART DISEASE IN THE HUNTER REGION OF NEW SOUTH WALES, AUSTRALIA, 1979–1985
33 Citations1988Annette J. Dobson, Robert Gibberd +4 more
Findings in Australia differ from findings in New Zealand, where the decrease in ischemic heart disease mortality has been attributed to fewer sudden deaths, demonstrating the need for carefully standardized studies to gain insight into evolving patterns of heart disease in different populations.
Journal of Clinical EpidemiologyMyocardial infarction in Girona, Spain: Attack rate, mortality rate and 28-day case fatality in 1988
32 Citations1993Glòria Pérez, Jaume Marrugat +1 more
Attack and mortality rates of AMI in a region of Spain are presented for the first time, and these rates are lower than in other developed countries, nevertheless the 28-day case-fatality is similar to that of these countries.
Journal of Epidemiology & Community HealthAsymptomatic hyperglycaemia and major ischaemic heart disease events in Britain.
28 Citations1994Ivan J. Perry, S. Goya Wannamethee +2 more
It is suggested that asymptomatic hyperglycaemia is an independent risk factor for major ischaemic heart disease events.
PubMedIncidence, delay and survival in the Belfast MONICA Project coronary event register.
11 Citations1990A. E. Evans, C. C. Patterson +3 more
During the 1983-85 period, the Belfast MONICA Project registered coronary events in 2,512 individuals (1,913 men and 599 women); there were statistically significant differences in the age and sex-standardised rates for the 107 electoral wards of the Study.