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Comparison of Oral Fluconazole and Itraconazole for Progressive, Nonmeningeal Coccidioidomycosis

Annals of Internal MedicinePublished 7 November 2000
John N. Galgiani, Antonino Catanzaro, Gretchen A. Cloud, Royce H. Johnson, Paul L. Williams, Laurence F. Mirels
Citations288
SJR quartileQ1
SJR score3.38
SNIP3.27

TL;DR

The findings from Mycoses Study Group Protocol 20, a comparative trial sponsored by the National Institute of Allergy and Infectious Diseases that compares two antifungal agents, fluconazole and itraconazole, in the treatment of coccidioidomycosis, are presented.

Abstract

Neither fluconazole nor itraconazole showed statistically superior efficacy in nonmeningeal coccidioidomycosis, although there is a trend toward slightly greater efficacy with itraconazole at the doses studied.

Keywords

Medicine