Unique High Affinity Uptake Systems for Glycine, Glutamic and Aspartic Acids in Central Nervous Tissue of the Rat
NaturePublished 1 December 1971
William J. Logan, Solomon H. Snyder
Citations295
SJR quartileQ1
SJR score18.29
SNIP10.16
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TL;DR
Experiments suggest that several aminoacids, especially glycine and glutamic, aspartic and gamma-aminobutyric acids are neurotransmitters in the central nervous system, but careful subcellular and regional studies have not provided supporting neurochemical evidence.
Abstract
NEUROPHYSIOLOGICAL experiments suggest that several aminoacids, especially glycine and glutamic, aspartic and gamma-aminobutyric (GABA) acids, are neurotransmitters in the central nervous system1–3. But careful subcellular4,5 and regional studies6–8 have not provided supporting neurochemical evidence, because ammo-acids, with the possible exception of GABA, also have general metabolic functions in nervous tissue.
Keywords
MedicineAgricultural and Biological SciencesNeuroscience
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