Correlation Between Prognostic Factors and Increasing Age in Melanoma
Annals of Surgical OncologyPublished 1 March 2004
Celia Chao, Robert C.G. Martin, Merrick I. Ross, Douglas S. Reintgen, Michael J. Edwards, R. Dirk Noyes
Citations219
SJR quartileQ1
SJR score1.15
SNIP1.09
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TL;DR
As age increases, so does Breslow thickness, the incidence of ulceration and regression, and the proportion of male patients—all poor prognostic factors; however, the frequency of SLN metastasis declines with increasing age, and this represents a decreased sensitivity of the SLN procedure in older patients.
Abstract
As age increases, so does Breslow thickness, the incidence of ulceration and regression, and the proportion of male patients-all poor prognostic factors. However, the frequency of SLN metastasis declines with increasing age. It is not known whether this represents a decreased sensitivity (higher false-negative rate) of the SLN procedure in older patients or a different biological behavior (hematogenous spread) of melanomas in older patients.
Keywords
Immunology and MicrobiologyMedicine
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