Influence of hospital volume on the frequency of abdominoperineal resections and long-term oncological outcomes in low rectal cancer
European Journal of Surgical OncologyPublished 5 February 2007
H. Ptok, F. Marusch, Ralf Kühn, I. Gastinger, H. Lippert, THESTUDYGROUPCOLONRECTUMCAR
Citations64
SJR quartileQ1
SJR score1.15
SNIP1.25
Generate an AI Snapshot to get a quick, structured summary of this paper.
Study Snapshot
ObjectiveStudy objective
MethodsResearch methodology
PopulationPopulation studied
Sample sizeSample sizes
OutcomesStudy outcomes here
ResultsStudy results comes here
LimitationsResearch study limitations comes here
A concise AI-generated summary of the paper will appear here once you click Generate AI Snapshot.
TL;DR
In the surgical treatment of low rectal cancer the hospital volume has a major impact on outcome, while the type of procedure does not affect the local recurrence rate but the disease free survival.
Abstract
In the surgical treatment of low rectal cancer the hospital volume has a major impact on outcome. The type of procedure does not affect the local recurrence rate but the disease free survival.
Keywords
Medicine
British journal of surgeryThe mesorectum in rectal cancer surgery—the clue to pelvic recurrence?
2,914 Citations1982Richard J. Heald, E M Husband +1 more
Five cases are described where minute foci of adenocarcinoma have been demonstrated in the mesorectum several centimetres distal to the apparent lower edge of a rectal cancer, and these operations have been carried out as a part of over 100 consecutive anterior resections.
The LancetRECURRENCE AND SURVIVAL AFTER TOTAL MESORECTAL EXCISION FOR RECTAL CANCER
2,718 Citations1986Richard J. Heald, R. D. H. Ryall
On this evidence, it is often safe to limit mural clearance and thus preserve the anal sphincters, provided that the mesorectum is excised intact with the cancer.
The LancetLOCAL RECURRENCE OF RECTAL ADENOCARCINOMA DUE TO INADEQUATE SURGICAL RESECTION
1,974 Citations1986Philip Quirke, Michael F. Dixon +2 more
In 52 patients with rectal adenocarcinoma whole-mount sections of the entire operative specimen were examined by transverse slicing, there was spread to the lateral resection margin in 14 of 52 patients and 12 of these proceeded to local pelvic recurrence.
Journal of Clinical OncologyMacroscopic Evaluation of Rectal Cancer Resection Specimen: Clinical Significance of the Pathologist in Quality Control
925 Citations2002Irıs D. Nagtegaal, Cornelis J.�H. van de Velde +4 more
British journal of surgeryPrognostic significance of the circumferential resection margin following total mesorectal excision for rectal cancer
672 Citations2002Arne Wibe, P R Rendedal +5 more
This study examined the prognostic impact of the circumferential resection margin on local recurrence, distant metastasis and survival rates.
Journal of Clinical OncologyLow Rectal Cancer: A Call for a Change of Approach in Abdominoperineal Resection
571 Citations2005Irıs D. Nagtegaal, C.J.H. van de Velde +3 more
The poor prognosis of the patients with an APR is ascribed to the resection plane of the operation leading to a high frequency of margin involvement by tumor and perforation with this current surgical technique.
Annals of SurgerySurgeon-Related Factors and Outcome in Rectal Cancer
569 Citations1998Geoffrey A. Porter, Colin L. Soskolne +2 more
Outcome is improved with both colorectal surgical subspecialty training and a higher frequency ofrectal cancer surgery, and the surgical treatment of rectal cancer patients should rely exclusively on surgeons with such training or surgeons with more experience.
Annals of SurgeryThe Modern Abdominoperineal Excision
427 Citations2005R. Marr, K Birbeck +12 more
Patients treated by APR have a higher rate of CRM involvement, a higher LR, and poorer prognosis than AR, and a more radical operation should be considered for all low rectal cancer tumors.
Diseases of the Colon & RectumOncological Outcomes After Total Mesorectal Excision for Cure for Cancer of the Lower Rectum: Anterior vs. Abdominoperineal Resection
422 Citations2004Arne Wibe, Astri Syse +4 more
In addition to patient and tumor characteristics (T4 tumors), intraoperative bowel perforation and tumor involvement of the circumferential margin were identified as significant prognostic factors, which were more common in the lower rectum, explaining the inferior prognosis for tumors in this region.
Annals of SurgerySphincter-Saving Resection for All Rectal Carcinomas
363 Citations2005Éric Rullier, Alexis Laurent +4 more
Tumor distance from the anal verge is no longer a limit for sphincter-saving resection and the technique of intersphincteric resection permits us to achieve conservative surgery in patients with a tumor close to or in the anal canal without compromising local control and survival.
Annals of SurgeryHospital and Surgeon Procedure Volume as Predictors of Outcome Following Rectal Cancer Resection
350 Citations2002Deborah Schrag, Katherine S. Panageas +5 more
Surgeon-specific experience as measured by procedure volume can have a significant impact on survival for patients with rectal cancer.
Diseases of the Colon & RectumAbdominoperineal excision of the rectum—An endangered operation
268 Citations1997Richard J. Heald, M. Chir +4 more
In a unit specializing in sphincter conservation, precise total mesorectal excision from above appears oncologically superior to abdominoperineal excisions.
International Journal of Radiation Oncology*Biology*PhysicsRadiotherapy does not compensate for positive resection margins in rectal cancer patients: report of a multicenter randomized trial
258 Citations2003Corrie A.M. Marijnen, Irıs D. Nagtegaal +6 more
Preoperative hypofractionated radiotherapy has a beneficial effect in patients with wide or narrow resection margins, but cannot compensate for microscopically irradical resections resulting in positive margins.
Diseases of the Colon & RectumTechnique and Long-Term Results of Intersphincteric Resection for Low Rectal Cancer
203 Citations2005R Schiessel, Gabriele Novi +6 more
Intersphincteric resection is a valuable procedure for sphincter-saving rectal surgery and showed that this technique has satisfactory long-term results in functional and oncologic respects.
British journal of surgeryInadvertent perforation during rectal cancer resection in Norway
151 Citations2004Morten Eriksen, Arne Wibe +3 more
The purpose of this study was to examine intraoperative perforation following the introduction of mesorectal excision as a standard surgical technique in Norway.
Journal of Clinical OncologyImpact of Hospital Procedure Volume on Surgical Operation and Long-Term Outcomes in High-Risk Curatively Resected Rectal Cancer: Findings From the Intergroup 0114 Study
139 Citations2003Jeffrey A. Meyerhardt, Joel E. Tepper +11 more
Hospital surgical volume had no significant effect on rectal cancer recurrence or survival when patients completed standard adjuvant therapy, and Sphincter-preserving surgery was more commonly performed at high-volume centers.
British journal of surgeryEffect of hospital caseload on long-term outcome after standardization of rectal cancer surgery at a national level
126 Citations2004Arne Wibe, Morten Eriksen +4 more
The purpose of this prospective study was to examine the influence of hospital caseload on long‐term outcome following standardization of rectal cancer surgery at a national level.
Diseases of the Colon & RectumVariations in treatment of rectal cancer
107 Citations1997Anthony Simons, Rhonda Ker +7 more
Surgical choices in the treatment of rectal cancer may vary widely, even in a well-defined geographic region, and hospital environment and surgical caseload experience seem to have a significant role in the choice of surgical procedure and on survival.
British journal of surgeryHospital caseload and the results achieved in patients with rectal cancer
98 Citations2001F. Marusch, A. Koch +4 more
The aim of the study was to investigate the impact of hospital caseload on the short‐term postoperative outcome of patients with rectal carcinoma.
Annals of Surgical OncologyProspective Evaluation of Quality of Life of Patients Receiving Either Abdominoperineal Resection or Sphincter-Preserving Procedure for Rectal Cancer
84 Citations2005Christian Schmidt, Beate Bestmann +3 more
Diseases of the Colon & RectumOutcomes for Abdominoperineal Resections Are Not Worse Than Those of Anterior Resections
73 Citations2005Esther W. L. Chuwa, Francis Seow‐Choen
Both abdominoperineal resections and sphincter-preserving anterior resections can be performed safely with low morbidity and mortality in a specialized high-volume hospital unit without compromising oncologic outcomes.
Diseases of the Colon & RectumTotal Mesorectal Excision for Rectal Cancer: Difference in Outcome for Low and High Rectal Cancer
67 Citations2005Arne E. Færden, Nazir Naimy +6 more
SSurgery alone for rectal cancer can achieve overall good results, with five-year overall survival of 72 percent and the prognosis of the cancers of the lower rectum seems to be inherently different from the tumors of the higher level, both concerning local recurrence and five- year survival.
Diseases of the Colon & RectumRelationship Between Surgeon Caseload and Sphincter Preservation in Patients With Rectal Cancer
64 Citations2005Harriett Purves, Ricardo Pietrobon +4 more
This analysis suggests that rectal cancer patients treated by high-volume surgeons are five times more likely to undergo sphincter-sparing procedures than those treated by low-volume surgeon.
Colorectal DiseaseHospital volume and outcome of rectal cancer surgery in Denmark 1994–99
62 Citations2004Henrik Harling, S Bülow +3 more
The outcome of rectal cancer surgery in Denmark during the period 1994–99 was analyzed to analyse the association between hospital volumen and outcome of major cancer surgery.
Der ChirurgProspektive Multizenterstudien “Kolon-/Rektumkarzinome” als flächendeckende chirurgische Qualitätssicherung
44 Citations2002Studiengruppe “Kolon-/Rektumkarzinome (Primärtumor)”, F. Marusch +9 more
A basis for a thorough and complete evaluation of colorectal carcinoma has been created and surgical quality control in the form of prospective multicentre observational studies is made possible.
World Journal of SurgeryAdequate distal margin of resection for adenocarcinoma of the rectum
36 Citations1992Robin Phillips
International Journal of Colorectal DiseaseResults of treatment of distal rectal carcinoma since the introduction of total mesorectal excision: a single unit experience, 1994?2003
25 Citations2004Antonio Chiappa, R. Biffi +13 more
With the practice of total mesorectal excision, APR was still necessary in 40% of patients with rectal cancer within 6 cm of the anal verge, and the local recurrence rate was lower in patients treated with APR than in those with double-stapled low anterior resection; however, survival rates were similar in these two groups.
European Journal of Surgical OncologyIs there still a place for abdominoperineal resection of the rectum?
23 Citations1995A. Glättli, Jean Pierre Barras +1 more
Preoperative staging measures are essential for patients selection in relation to height of the tumour above the anal canal, depth of tumour invasion into the rectal wall, and presence or absence of regional lymph node metastases.
Der ChirurgStellenwert der Rektumexstirpation im Therapiekonzept des tief sitzenden Rektumkarzinoms
22 Citations2003Studiengruppe “Kolon/Rektum Karzinome (Primärtumor)”, F. Marusch +12 more