Does ethanol enhance cocaine toxicity?

The findings suggest that acute cocaine toxicity is not enhanced by ethanol cocaine interactions, and it is possible that increased toxicity is apparent when much larger quantities of alcohol have been consumed.

Abstract

In two-thirds of the cocaine-related deaths studied, no ethanol was detected. When ethanol was present, no differences between the two groups were identified. The findings suggest that acute cocaine toxicity is not enhanced by ethanol cocaine interactions. However, ethanol concentrations were generally low, and it is possible that increased toxicity is apparent when much larger quantities of alcohol have been consumed.