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Insulin secretory responses to rising and falling glucose concentrations are delayed in subjects with impaired glucose tolerance

DiabetologiaPublished 1 April 2002Open access
David A. Ehrmann, Elena Breda, Melissa K. Cavaghan, S. Bajramovic, Jacqueline Imperial, Gianna Toffolo
Citations43
SJR quartileQ1
SJR score3.62
SNIP2.67
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TL;DR

Beta-cell responses to changes in glucose would not be normal in subjects with impaired glucose tolerance (IGT) and subjects with IGT show delays in the timing of the beta-cell response to glucose when glucose levels are either rising or falling.

Abstract

Subjects with IGT are not able to secrete insulin to compensate adequately for insulin resistance. They also show delays in the timing of the beta-cell response to glucose when glucose levels are either rising or falling.

Keywords

MedicineNeuroscience