BONE-MARROW TRANSPLANTATION IN A PATIENT WITH THE WISKOTT-ALDRICH SYNDROME
The LancetPublished 1 December 1968
F H Bach, RichardJ. Albertini, Patricia Joo, JamesL. Anderson, M. M. Bortin
Citations863
SJR quartileQ1
SJR score12.11
SNIP22.72
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Abstract
A 2-year-old boy with the Wiskott-Aldrich syndrome has been treated by bone-marrow transplantation. An initial attempt to transplantation without extensive preparation of the recipient failed. Subsequently the recipient was prepared with a 4-day course of cyclophosphamide followed by bone-marrow transplantation from a sister identical at HL-A— the major histocompatibility locus in man. 6 weeks after transplantation the patient is chimaric and has shown no evidence of graft-versus-host disease.
Keywords
MedicineBiochemistry, Genetics and Molecular Biology
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