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Breast cancer in women ≤35 years: Review of 1002 cases from a single institution

Annals of OncologyPublished 1 October 2000
Andrew K. Chan, Melania Pintilie, Katherine A. Vallis, C. Girourd, Paul E. Goss
Citations76
SJR quartileQ1
SJR score19.07
SNIP10.48

TL;DR

In this cohort, breast cancer was usually self-diagnosed and tumors were > 2 cm at presentation in approximately two-thirds of cases, suggesting the possibilities of a delay in diagnosis, more aggressive tumors or both.

Abstract

In this cohort, breast cancer was usually self-diagnosed and tumors were > 2 cm at presentation in approximately two-thirds of cases, suggesting the possibilities of a delay in diagnosis, more aggressive tumors or both. Our results are compatible with the known association of breast cancer FH with increased CBC. Our data also corroborates the suggestion that positive genetic testing in this age group should lead to consideration of more aggressive ipsilateral and contralateral breast management. In those receiving adjuvant irradiation after BCS, the LR rate was high, but did not impact on overall survival.

Keywords

Biochemistry, Genetics and Molecular Biology