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Distribution and origins of substance P (SP)-, calcitonin gene-related peptide (CGRP)-, vasoactive intestinal polypeptide (VIP)- and neuropeptide Y (NPY)-containing nerve fibers in the pineal gland of gerbils

Neuroscience LettersPublished 1 October 1986
Yahē Shiotani, Mariko Yamano, Sadao Shiosaka, Piers C. Emson, Carmel J. Hillyard, Samia I. Girgis
Citations103
SJR quartileQ2
SJR score0.77
SNIP0.67

TL;DR

In the pineal gland of gerbils, substance P (SP)-, calcitonin gene-related peptide (CGRP)-, vasoactive intestinal polypeptide (VIP)- and neuropeptides Y (NPY)-containing nerve fibers were demonstrated immunohistochemically and confirmed that SP- and CGRP-fibers originated from the trigeminal ganglion.

Abstract

In the pineal gland of gerbils, substance P (SP)-, calcitonin gene-related peptide (CGRP)-, vasoactive intestinal polypeptide (VIP)- and neuropeptide Y (NPY)-containing nerve fibers were demonstrated immunohistochemically. After intrapineal injection of biotin-wheat germ agglutinin, origins of fibers were examined by the combined technique of tracing method and immunohistochemistry. It was confirmed that SP- and CGRP-fibers originated from the trigeminal ganglion, VIP-fibers from the pterygopalatine ganglion and NPY-fibers from the superior cervical ganglion.

Keywords

MedicineNeuroscienceBiochemistry, Genetics and Molecular Biology