Monkey see, monkey do
Nature GeneticsPublished 27 June 2006
Benjamin Prud’homme, Sean B. Carroll
Citations24
SJR quartileQ1
SJR score16.59
SNIP6.64
Generate an AI Snapshot to get a quick, structured summary of this paper.
Study Snapshot
ObjectiveStudy objective
MethodsResearch methodology
PopulationPopulation studied
Sample sizeSample sizes
OutcomesStudy outcomes here
ResultsStudy results comes here
LimitationsResearch study limitations comes here
A concise AI-generated summary of the paper will appear here once you click Generate AI Snapshot.
TL;DR
It is shown that the independent adaptation to a ruminant lifestyle in two leaf-eating monkeys relied on parallel amino acid substitutions in ribonuclease gene duplicates, suggesting that proteins may repeatedly follow similar adaptive evolutionary paths.
Abstract
A new study shows that the independent adaptation to a ruminant lifestyle in two leaf-eating monkeys relied on parallel amino acid substitutions in ribonuclease gene duplicates. This discovery suggests that, given similar initial conditions, proteins may repeatedly follow similar adaptive evolutionary paths.
Keywords
Social SciencesBiochemistry, Genetics and Molecular Biology
ScienceDarwinian Evolution Can Follow Only Very Few Mutational Paths to Fitter Proteins
1,528 Citations2006Daniel Weinreich, Nigel F. Delaney +2 more
It is demonstrated that 102 mutational trajectories linking β-lactamase alleles are inaccessible to Darwinian selection and that many of the remaining trajectories have negligible probabilities of realization, which implies that the protein tape of life may be largely reproducible and even predictable.
Nature MedicineOrdered accumulation of mutations in HIV protease confers resistance to ritonavir
766 Citations1996Akhteruzzaman Molla, Marina Korneyeva +15 more
Analysis of the HIV protease gene from the plasma of HIV–infected patients revealed substitutions at nine different codons selected in response to monotherapy with the protease inhibitors ritonavir, suggesting that dual protease inhibitor therapy might increase the duration of viral suppression.
Nature Reviews GeneticsMissense meanderings in sequence space: a biophysical view of protein evolution
663 Citations2005Mark A. DePristo, Daniel Weinreich +1 more
This work reviews the literature on biophysics as it relates to molecular evolution and advances a biophysical model of protein evolution that helps to understand phenomena that range from the dynamics of molecular adaptation to the clock-like rate ofprotein evolution.
Nature GeneticsGenetic analysis of cavefish reveals molecular convergence in the evolution of albinism
540 Citations2005Meredith Protas, Candace Hersey +7 more
The generation of a genome-wide linkage map is described to allow quantitative trait analysis of evolutionarily derived morphologies in the Mexican cave tetra, a species that has, in a series of independent caves, repeatedly evolved specialized characteristics adapted to a unique and well-studied ecological environment.
Choice Reviews OnlineLife's solution: inevitable humans in a lonely universe
530 Citations2004
The Cambridge Sandwich considers life as a cosmic principle, the ubiquity of convergence, and the role of theology in the story of evolution.
NatureRepeated morphological evolution through cis-regulatory changes in a pleiotropic gene
521 Citations2006Benjamin Prud’homme, Nicolas Gompel +6 more
It is shown that a male wing pigmentation pattern involved in courtship display has been gained and lost multiple times in a Drosophila clade, demonstrating how the functional diversification of the modular CREs of pleiotropic genes contributes to evolutionary novelty and the independent evolution of morphological similarities.
GeneticsExceptional Convergent Evolution in a Virus
385 Citations1997James J. Bull, M. R. Badgett +6 more
Replicate lineages of the bacteriophage phiX 174 adapted to growth at high temperature on either of two hosts exhibited high rates of identical, independent substitutions, which were higher during the initial period of adaptation than during a later period, except when the host was changed.
Nature GeneticsAdaptive evolution of a duplicated pancreatic ribonuclease gene in a leaf-eating monkey
370 Citations2002Jianzhi Zhang, Ya-Ping Zhang +1 more
NatureIndependent evolution of bitter-taste sensitivity in humans and chimpanzees
210 Citations2006Stephen Wooding, Bernd Bufe +8 more
Nature GeneticsParallel adaptive origins of digestive RNases in Asian and African leaf monkeys
207 Citations2006Jianzhi Zhang
It is reported that the gene encoding pancreatic ribonuclease was duplicated independently in Asian and African leaf-eating monkeys, demonstrating that despite the overall stochasticity, even molecular evolution has a certain degree of repeatability and predictability under the pressures of natural selection.
Proceedings of the National Academy of SciencesMolecular analysis of the evolutionary significance of ultraviolet vision in vertebrates
184 Citations2003Yongsheng Shi, Shozo Yokoyama
The use of UV vision is associated strongly with UV-dependent behaviors of organisms, and the SWS1 gene can become nonfunctional when UV light is not available or is unimportant to organisms, as exemplified by coelacanth and dolphin.
Vision ResearchMolecular evolution of trichromacy in primates
156 Citations1998David M. Hunt, Kanwaljit S. Dulai +6 more
The separate origin of the trichromacy in New and Old World primates would indicate that the selection of these three sites is the result of convergent evolution, perhaps as a consequence of visual adaptation in both cases to foraging for yellow and orange fruits against a green foliage.
Choice Reviews OnlineThe making of the fittest: DNA and the ultimate forensic record of evolution
86 Citations2007
The Making and Evolution of Complexity is a posthumous publication based on a manuscript originally written by Gordon C. Dickinson in 2013 and then edited by David I. Dickinson.
Molecular Biology and EvolutionParallel Functional Changes in the Digestive RNases of Ruminants and Colobines by Divergent Amino Acid Substitutions
55 Citations2003Xiaofeng Zhang
The results suggest that (1) an evolutionary problem can have multiple solutions, (2) the same amino acid substitution may have opposite functional effects in homologous proteins, (3) the stochastic processes of mutation and drift play an important role even at functionally important sites, and (4) protein sequences may diverge even when their functions converge.