A Powerful Chiral Counteranion Motif for Asymmetric Catalysis
Angewandte Chemie International EditionPublished 13 May 2009Open access
Pilar Garcı́a Garcı́a, Frank Lay, Patricia García‐García, Constantinos Rabalakos, Benjamin List
Citations277
SJR quartileQ1
SJR score5.55
SNIP2.47
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TL;DR
A chiral disulfonimide has been designed as a powerful new motif for asymmetric catalysis and a highly efficient and enantioselective Mukaiyama aldol reaction has been developed.
Abstract
Room to swing a cat: A chiral disulfonimide has been designed as a powerful new motif for asymmetric catalysis. As a first illustration, a highly efficient and enantioselective Mukaiyama aldol reaction has been developed (see scheme). The actual catalyst is proposed to be an N-silyl imide which is generated in situ.
Keywords
Chemistry
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