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ADENOSINE TRIPHOSPHATE-LINKED CONCENTRATION OF CALCIUM IONS IN A PARTICULATE FRACTION OF RABBIT MUSCLE

The Journal of Cell BiologyPublished 1 September 1962Open access
Setsuro Ebashi, Fritz Lipmann
Citations707
SJR quartileQ1
SJR score3.36
SNIP1.52
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TL;DR

ATPase and ATP-dependent calcium ion concentration was studied with a membrane fraction isolated from homogenized rabbit skeletal muscle by differential centrifugation, indicating that it consists mainly of resealed tubules and vesicles of the endoplasmic reticulum.

Abstract

ATPase and ATP-dependent calcium ion concentration was studied with a membrane fraction isolated from homogenized rabbit skeletal muscle by differential centrifugation. Electron micrographs of the fraction indicate that it consists mainly of resealed tubules and vesicles of the endoplasmic reticulum. The up-to-1400-fold concentration of calcium in this fraction might be explained by proposing the existence of an energy-requiring system for the transport of calcium ions into the tubules or vesicles.

Keywords

ChemistryMedicineBiochemistry, Genetics and Molecular Biology