Role of individual, peer and family factors in the use of cannabis and other illicit drugs: A longitudinal analysis among Finnish adolescent twins
Drug and Alcohol DependencePublished 4 May 2008Open access
Tellervo Korhonen, Anja C. Huizink, Danielle M. Dick, Lea Pulkkinen, Robert M. Rose, Jaakko Kaprio
Citations107
Generate an AI Snapshot to get a quick, structured summary of this paper.
Study Snapshot
ObjectiveStudy objective
MethodsResearch methodology
PopulationPopulation studied
Sample sizeSample sizes
OutcomesStudy outcomes here
ResultsStudy results comes here
LimitationsResearch study limitations comes here
A concise AI-generated summary of the paper will appear here once you click Generate AI Snapshot.
TL;DR
Early onset smoking is a powerful predictor for subsequent use of illicit drugs among Finnish adolescents, but the causal nature of this relationship needs to be clarified.
Abstract
Early onset smoking is a powerful predictor for subsequent use of illicit drugs among Finnish adolescents, but the causal nature of this relationship needs to be clarified.
Keywords
PsychologyMedicine
Psychological BulletinRisk and protective factors for alcohol and other drug problems in adolescence and early adulthood: Implications for substance abuse prevention.
5,309 Citations1992J. David Hawkins, Richard F. Catalano +1 more
The authors suggest that the most promising route to effective strategies for the prevention of adolescent alcohol and other drug problems is through a risk-focused approach.
BiometricsA Note on Robust Variance Estimation for Cluster‐Correlated Data
2,523 Citations2000Rick L. Williams
This brief note presents a general proof that the estimator is unbiased for cluster-correlated data regardless of the setting.
The LancetCannabis use and risk of psychotic or affective mental health outcomes: a systematic review
2,205 Citations2007Theresa HM Moore, Stanley Zammit +5 more
There is now sufficient evidence to warn young people that using cannabis could increase their risk of developing a psychotic illness later in life, although evidence for affective outcomes is less strong.
Biological PsychiatryModeration of the Effect of Adolescent-Onset Cannabis Use on Adult Psychosis by a Functional Polymorphism in the Catechol-O-Methyltransferase Gene: Longitudinal Evidence of a Gene X Environment Interaction
1,410 Citations2005Avshalom Caspi, Terrie E. Moffitt +10 more
Findings provide evidence of a gene x environment interaction and suggest that a role of some susceptibility genes is to influence vulnerability to environmental pathogens.
BMJCannabis use in adolescence and risk for adult psychosis: longitudinal prospective study
1,405 Citations2002Louise Arseneault, Mary Cannon +4 more
This is the first prospective longitudinal study of adolescent cannabis use as a risk factor for adult schizophreniform disorder, taking into account childhood psychotic symptoms, and the Dunedin multidisciplinary health and development study has a 96% follow up rate at age 26.
Nature NeuroscienceGenetic influences on impulsivity, risk taking, stress responsivity and vulnerability to drug abuse and addiction
1,028 Citations2005Mary Jeanne Kreek, David A. Nielsen +2 more
This work focuses on recent approaches to the study of genetic variation in personality and physiological traits, and their influence on and interaction with addictive diseases.
The British Journal of PsychiatryCausal association between cannabis and psychosis: examination of the evidence
921 Citations2004Louise Arseneault, Mary Cannon +2 more
Cases of psychotic disorder could be prevented by discouraging cannabis use among vulnerable youths and research is needed to understand the mechanisms by which cannabis causes psychosis.
JAMAEscalation of Drug Use in Early-Onset Cannabis Users vs Co-twin Controls
637 Citations2003Michael T. Lynskey, Andrew C. Heath +6 more
JAMAPrevalence of Marijuana Use Disorders in the United States
534 Citations2004Wilson M. Compton, Bridget F. Grant +3 more
Despite the stability in the overall prevalence of marijuana use, more adults in the United States had a marijuana use disorder in 2001-2002 than in 1991-1992 and the results of this study underscore the need to develop and implement new prevention and intervention programs targeted at youth.
Archives of General PsychiatryDrug Use and the Risk of Major Depressive Disorder, Alcohol Dependence, and Substance Use Disorders
528 Citations2002David W. Brook, Judith S. Brook +3 more
The results suggest that early drug use is associated with and predicts later psychiatric disorders and preventive implications stem from the importance of studying a range of psychiatric disorders in the context of substance use assessed over a wide age range.
Journal of Psychiatric ResearchSpecificity of social anxiety disorder as a risk factor for alcohol and cannabis dependence
507 Citations2007Julia D. Buckner, Norman B. Schmidt +4 more
Among the internalizing disorders, SAD appears to serve as a unique risk factor for the subsequent onset of cannabis and alcohol dependence, after controlling for theoretically-relevant variables.
Drug and Alcohol ReviewMental health and alcohol, drugs and tobacco: a review of the comorbidity between mental disorders and the use of alcohol, tobacco and illicit drugs
495 Citations2006Eva Jané‐Llopis, Irina Matytsina
There is a need to expand the evidence base on comorbidity, particularly in low-income countries, and policies that reduce the use of substances are likely to reduce the prevalence of mental disorders.
American Journal of Public HealthFrom beer to crack: developmental patterns of drug involvement.
489 Citations1993Denise B. Kandel, Kazuo Yamaguchi
The developmental pattern of drug involvement identified in the early 1970s still characterizes adolescent pathways of drug involved in the late 1980s and the results confirm the more important role of alcohol among males and cigarettes among females in the progression into various drug classes.
Neuroscience & Biobehavioral ReviewsMaternal smoking, drinking or cannabis use during pregnancy and neurobehavioral and cognitive functioning in human offspring
467 Citations2005Anja C. Huizink, E Mulder
It is concluded that prenatal exposure to either maternal smoking, alcohol or cannabis use is related to some common neurobehavioral and cognitive outcomes, including symptoms of ADHD, increased externalizing behavior, decreased general cognitive functioning, and deficits in learning and memory tasks.
Journal of the American Academy of Child PsychiatryEpidemiological and Psychosocial Perspectives on Adolescent Drug Use
353 Citations1982Denise B. Kandel
Despite dramatic increases in the use of marijuana in American society over the last decade, youths who use marijuana in 1980 show the same pattern of disaffection from major institutions as users in 1967.
Drug and Alcohol DependenceCannabis use and cannabis use disorders and their relationship to mental disorders: A 10-year prospective-longitudinal community study in adolescents
313 Citations2007Hans‐Ulrich Wïttchen, Christine Fröhlich +6 more
Twin ResearchGenetic and Environmental Factors in Health-related Behaviors: Studies on Finnish Twins and Twin Families
284 Citations2002Jaakko Kaprio, Lea Pulkkinen +1 more
Statistical Methods in Genetic Epidemiology
283 Citations2004Duncan C. Thomas
Tying it all together: the genetic epidemiology of colorectal cancer Glossary shows how basic epidemiologic and statistical principles, as well as basic concepts of molecular genetics, can be applied to population genetics.
Harvard Review of PsychiatryThe Harvard Twin Study of Substance Abuse: What We Have Learned
271 Citations2001Ming T. Tsuang, Jessica L. Bar +2 more
It is found that the co-occurrence of illicit drug abuse and major depression is due to unique environmental influences, and the phenotypic association between symptoms of conduct disorder and alcohol and marijuana dependence is due largely to shared environmental influences.
Alcoholism Clinical and Experimental ResearchGene‐Environment Interaction in Patterns of Adolescent Drinking: Regional Residency Moderates Longitudinal Influences on Alcohol Use
246 Citations2001Richard J. Rose, Danielle M. Dick +2 more
It is revealed that genetic factors influencing drinking patterns increased in importance across the 30-month period, and effects arising from common environmental influences declined, document the changing impact of genetic and environmental influences on alcohol use across adolescence.
Journal of the American Academy of Child & Adolescent PsychiatryYoung Adult Drug Use and Delinquency: Childhood Antecedents and Adolescent Mediators
227 Citations1996Judith S. Brook, Martin Whiteman +2 more
The findings indicated that childhood aggression was related to both young adult drug use and delinquency and drug use during early adolescence had an impact on delinquency not only in early adolescence, but also in late adolescence and young adulthood.
AddictionThe genetic epidemiology of cannabis use, abuse and dependence
215 Citations2006Arpana Agrawal, Michael T. Lynskey
The substantial evidence for the heritability of cannabis use, abuse and dependence underscore the importance of linkage and association studies that aim to find genes of etiologic significance.
Psychology of Addictive BehaviorsPsychopathology as a predictor of adolescent drug use trajectories.
193 Citations2001Helene R. White, Minge Xie +3 more
The authors examine early psychopathology as a predictor of trajectories of drug use from ages 13-18 years and suggest that drug use prevention programs should target youths with early symptoms of psychopathology.
Drug and Alcohol DependencePersonality, substance of choice, and polysubstance involvement among substance dependent patients
182 Citations2003Kevin P. Conway, Robert J. Kane +3 more
It is found that patients who were dependent on two or more substances displayed higher levels of TCI-NS, CPI-Soc, and MAC, and an association between behavioral disinhibition and a continuum of addiction defined primarily in terms of polysubstance involvement is implicate.
AddictionPrenatal marijuana exposure contributes to the prediction of marijuana use at age 14
162 Citations2006Nancy L. Day, Lidush Goldschmidt +1 more
Prenatal exposure to marijuana, in addition to other factors, is a significant predictor of marijuana use at age 14, after controlling for other variables.
Journal of Abnormal Child PsychologyThe importance of conduct problems and depressive symptoms in predicting adolescent substance use
162 Citations1993Bill Henry, Mike Feehan +4 more
Both conduct problems and depressive symptoms at age 15 were also found to be associated with concurrent “self-medication” among females and the strongest association between predictors and substance use emerged between age 15 multiple drug use and concurrent conduct problems for both males and females.
Alcoholism Clinical and Experimental ResearchDrinking or Abstaining at Age 14? A Genetic Epidemiological Study
161 Citations2001Richard J. Rose, Danielle M. Dick +3 more
Environmental factors shared by twin siblings account for most of the variance in abstaining or drinking at age 14, and predictors of drinking in the adolescent twins' home environments and in their dispositional behaviors, sibling interactions, and pubertal timing are identified.
American Journal of PsychiatryDevelopments in the Epidemiology of Drug Use and Drug Use Disorders
150 Citations2005Wilson M. Compton, Yonette F. Thomas +2 more
The next challenges for the epidemiology of drug use and drug use disorders will be to link individual vulnerabilities with specific environmental factors by using multilevel methodological approaches.
Journal of Child Psychology and PsychiatrySubstance Abuse in Young People
144 Citations2000Éilish Gilvarry
The evidence tends to support multi faceted interventions for high risk youths, however, the use of evidence based programmes with a scientific basis should be supported and implemented.
American Journal of PsychiatryPredictors of Marijuana Use in Adolescents Before and After Licit Drug Use: Examination of the Gateway Hypothesis
142 Citations2006Ralph E. Tarter
Proneness to deviancy and drug availability in the neighborhood promote marijuana use and support the common liability model of substance use behavior and substance use disorder.
Preventive MedicineRisk for initiation of substance use as a function of age of onset of cigarette, alcohol and cannabis use: Findings in a Midwestern female twin cohort
115 Citations2006Arpana Agrawal, Julia D. Grant +7 more
Women who initiated cigarette, alcohol or cannabis use at an early age were at elevated risk for early experimentation with each subsequent drug class, and early-onset of more than one substance contributed greater risk for initiation of subsequent drugs.
Twin Research and Human GeneticsTwin Studies in Finland 2006
111 Citations2006Jaakko Kaprio
Current, ongoing data collection and analyses of longitudinal studies of adolescent twins and their families have focused on determinants of health-related behaviors and disease in adolescents and young adults are described.
American Journal of PsychiatryPredictors of Marijuana Use in Adolescents Before and After Licit Drug Use: Examination of the Gateway Hypothesis
109 Citations2006Ralph E. Tarter, Michael M. Vanyukov +3 more
Twin ResearchPeers, teachers and parents as assessors of the behavioural and emotional problems of twins and their adjustment: the Multidimensional Peer Nomination Inventory
102 Citations1999Lea Pulkkinen, Jaakko Kaprio +1 more
The British Journal of PsychiatryCannabis use and mental health in secondary school children
99 Citations2006Karin Monshouwer, Saskia van Dorsselaer +4 more
In a country with a liberal drug policy like The Netherlands, cannabis use is associated with aggression and delinquency, just as in other countries, but cannabis use was not associated with internalising problems.
AddictionRevisiting drug progression: long‐range effects of early tobacco use
92 Citations2005William A. Vega, Andrés G. Gil
Results indicated ethnic differences in rates and progression of tobacco use, with African Americans and foreign-born Latinos having larger proportions of abstainers and lower rates of persistent use.
Drug and Alcohol DependenceAge and sex differences in factors associated with the onset of cannabis use: a cohort study
91 Citations2006Mònica Guxens, Manel Nebot +1 more
The results support the role of tobacco and alcohol, as well as the influence of drug use among friends, and the importance of leisure time patterns as facilitators of cannabis use.
Gaceta SanitariaFactors associated with the onset of cannabis use: a systematic review of cohort studies
90 Citations2007Mònica Guxensa, Manel Nebot +2 more
The factors of great evidence related to the onset of cannabis use were masculine sex, consumption of tobacco or alcohol, having a problematic relationship with parents, and cannabis consumption by friends.
Data Archiving and Networked Services (DANS)Friends, lovers, and groups : key relationships in adolescence
85 Citations2007Rutger C. M. E. Engels, Margaret Kerr +1 more
BMJSymptoms of anxiety and depression in childhood and use of MDMA: prospective, population based study
77 Citations2006Anja C. Huizink, Robert F. Ferdinand +2 more
Individuals with childhood symptoms of anxiety and depression may have an increased tendency to use MDMA in adolescence or young adulthood, especially individuals with symptoms of Anxiety or depression.
AddictionInattentiveness, parental smoking and adolescent smoking initiation
72 Citations2004Satu K. Barman, Lea Pulkkinen +2 more
Inattentiveness and parental smoking additively predicted both experimental and current smoking in adolescence, and the probability of current smoking can rise as high as 38%, compared with 5% without these two risk factors.
PEDIATRICSInfluences of Parenting Practices on the Risk of Having a Chance to Try Cannabis
68 Citations2005Chuan‐Yu Chen, Carla L. Storr +1 more
The extent to which parental monitoring, parental involvement and reinforcement, and coercive parental discipline during primary school might exert a durable influence on the risk of transitioning into an early stage of youthful cannabis involvement, ie, the first chance to try cannabis is estimated.
Twin ResearchPeers, teachers and parents as assessors of the behavioural and emotional problems of twins and their adjustment: the Multidimensional Peer Nomination Inventory
64 Citations1999Lea Pulkkinen, Jaakko Kaprio +1 more
A multidimensional peer nomination inventory (MPNI) was developed during a major new Finnish study of families with twins, providing evidence of concurrent validity of peer-referenced assessment, using teacher assessments as criteria; correlations between assessments of peers and parents were lower.
Preventive MedicineCorrelates of cannabis initiation in a longitudinal sample of young women: The importance of peer influences
63 Citations2007Arpana Agrawal, Michael T. Lynskey +3 more
Having peers with favorable attitudes towards alcohol, cigarette and cannabis use is an important correlate of initiation of cannabis use in women, and prevention and intervention efforts need to take this into account when developing drug resistance training programs for adolescents.
Gaceta SanitariaFactores asociados al inicio del consumo de cannabis: una revisión sistemática de estudios de cohortes
55 Citations2007Mònica Guxens, Manel Nebot +2 more
Los resultados senalan la importancia de diversos factores individuales, familiares and del entorno en el inicio del consumo of cannabis, que deberian considerarse de forma conjunta en el abordaje preventivo entre los adolescentes.
Cambridge University Press eBooksSocioemotional Development and Health from Adolescence to Adulthood
54 Citations2006Lea Pulkkinen, Lea Pulkkinen +23 more
The Jyvaskyla longitudinal study of personality and social development (JYLS) and its implications for health and social behaviors and health in twins: the FinnTwin studies are presented.
The Journal of Clinical PharmacologyClinical Consequences of Marijuana
44 Citations2002Jag Khalsa, Sander Genser +2 more
Research presented in this special supplement will show that in addition to marijuana abuse/dependence, marijuana use is associated in some studies with impairment of cognitive function in the young and old, fetal and developmental consequences, cardiovascular effects, respiratory/pulmonary complications such as chronic cough and emphysema, and the risk of developing head, neck, and/or lung cancer.
Child Care Health and DevelopmentCausal association between cannabis and psychosis: examination of the evidence
44 Citations2004Richard Reading
Cases of psychotic disorder could be prevented by discouraging cannabis use among vulnerable youths and research is needed to understand the mechanisms by which cannabis causes psychosis.
Twin ResearchGenetic and Environmental Factors in Health-related Behaviors: Studies on Finnish Twins and Twin Families
40 Citations2002Jaakko Kaprio, Lea Pulkkinen +1 more
Twin and twin-family studies with multiple measurements of risk factors and morbidity over time can permit a much more detailed assessment of the developmental dynamics of disease risk and the unfolding of behavioral risk factors.
Behavior GeneticsThe Association between Conduct Problems and the Initiation and Progression of Marijuana Use during Adolescence: A Genetic Analysis across Time
29 Citations2006Katherine H. Shelton, Kate Lifford +6 more
Investigation of genetic and environmental influences on the association between earlier conduct problems and the initiation and progression of marijuana use during adolescence suggested that the initiation ofarijuana use in adolescence was influenced by genetic, common and unique environmental factors.
Drug and Alcohol DependenceCorrelates of initiation to cannabis use: a 5-year follow-up of 15–19-year-old adolescents
25 Citations2001Kari Poikolainen, Annamari Tuulio‐Henriksson +4 more
This initiation to cannabis was related to male gender, absence of mother, frequent lack of interest and early age at first sexual intercourse in logistic regression analysis, and these factors seem to be useful in predicting initiation to Cannabis.
American Journal of EpidemiologyAssociation of Maternal Smoking and Alcohol Consumption with Young Adults' Cannabis Use: A Prospective Study
25 Citations2007Mohammad R. Hayatbakhsh, Rosa Alati +6 more
It was found that maternalsmoking at 14 years was associated with frequent use of cannabis in offspring at 21 years, regardless of maternal smoking at 5 years, and the association was partially mediated by adolescent externalizing behavior and smoking measured at14 years.
Alcoholism Clinical and Experimental ResearchDrinking or Abstaining at Age 14? A Genetic Epidemiological Study
10 Citations2001Richard J. Rose, Danielle M. Dick +3 more
Peers, Parents, and Processes of Adolescent Socialization: A Twin–Study Perspective
6 Citations2006Richard J. Rose
Finland drug situation 2005 : 2005 national report to the EMCDDA by The Finnish National Focal Point
5 Citations2006Ari Virtanen
AddictionGENETIC EPIDEMIOLOGY OF CANNABIS USE, ABUSE AND DEPENDENCE: A COMMENT ON AGRAWAL & LYNSKEY (2006)
2 Citations2006Jaakko Kaprio
