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Failure of hypophysectomy to alter brain content of opioid peptides (endorphins)

Life SciencesPublished 1 October 1976
Alphonsus L. Cheung, Avram Goldstein
Citations73
SJR quartileQ1
SJR score1.31
SNIP1.07

TL;DR

Opioid peptides (endorphins) were extracted from brains of hypophysectomized rats and sham-operated controls and apparently, the brain endorphins do not come from the pituitary, but are probably synthesized in the brain.

Abstract

Opioid peptides (endorphins) were extracted from brains of hypophysectomized rats and sham-operated controls on the 34th post-operative day. There were no significant differences in endorphin content between groups. Evidently, the brain endorphins do not come from the pituitary, but are probably synthesized in the brain.

Keywords

MedicineNeuroscience